gene.4digits.result) if (length(HLA.gene.4digits.result)==0) { HLA.gene.4digits.result=NA } HLA.one_gene.result <- list(HLA.gene.2digits.result=HLA.gene.2digits.result, HLA.gene.4digits.result=HLA.gene.4digits.result) } # 主程序,获得每个样本每个基因的分型 for (s in colnames(...
In the second strategy, gene expression in the two conditions was compared by using a random sampling method for differential cloning, differential mRNA display. Surprisingly, none of the known mRNAs tested were altered significantly in the LGN upon 10 days of activity blockade. Differential mRNA ...
Hence, we used a multi-modal single-cell sequencing approach to analyze the expression of an established gene list of tissue repair-associated factors39,41 in colonic CD4 T cells that had been stimulated with either cytokines (IL-12 and IL-18), plate-bound anti-CD3 antibodies or a ...
MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions. However, there is a fundamental difference between the organization of class I genes in mammals and non-mammal...
5C,D). For example, the protein-coding gene DNTT, encoding the highest number of TSAs, was normally expressed in primitive hematopoietic cells and B-cell progenitors, whereas it was also over-expressed in older AML patients with NPM1 wild-type reported by previous studies34....
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MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions. However, there is a fundamental difference between the organizatio
There are three gene families for murine MHC class I: H‑2K, H‑2D and H‑2L and for human MHC: HLA‑A, HLA‑B and HLA‑C. The first step in CD8+ T cell generation is the uptake and presentation of peptides by antigen presenting cells through their MHC molecules. Peptide...
13 To validate this observation in silico, and assess more broadly whether the MHC-II gene family is suppressed in CML cells, we extended this gene list to include other relevant MHC-II molecules and identified a second, complementary data set14 in which we could perform GSEA17 of this MHC...
MHC class II alpha gene polymorphism and its association with resistance/susceptibility to Vibrio anguillarum in Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2010;34:1042–50. Article CAS PubMed Google Scholar Li H, Jiang L, Han J, Su H, Yang Q, He C. Major ...