Multifunctional nanoparticles for drug delivery applications imaging, targeting, and delivery. New York: Springer; 2012:48-55.Jain S, Amiji MM. Macrophage-targeted nanoparticle delivery systems. In: Svenson S, Prud'homme RK, editors. Multifunctional nanoparticles for drug delivery applications: imaging...
Additionally, we provide novel perspectives on how macrophage-targeting nanoparticles can deliver a broad range of therapeutic payloads to atherosclerotic lesions. These nanoparticles can suppress pro-atherogenic macrophage processes, leading to improved resolution of inflammation and stabilization of plaques. ...
These nanoparticles can accelerate bacteria-infected wound healing. In this work, nanoparticles were fabricated for bacteria-infected macrophage-targeted and microenvironment-responsive antibiotic delivery, cellular ROS generation, and proinflammatory up-regulation activity to eliminate intracellular bacteria, which...
Nanoparticles can also be synthesized with control over average size, size distribution, and particle shape, all key factors related to cellular uptake mechanisms and improved penetration across biological barriers. Additionally, some nanoparticles offer the possibility for combined use as therapeutic and ...
MM NPs: Macrophage membrane nanoparticles, H&E: Hematoxylin-eosin, and IHC: Immunohistochemistry Full size image Multiomics analysis of proteins in sEVs from patients with sepsis, and signaling pathway enrichment analysis of mouse liver and lung tissues In addition to miRNAs, EVs contain proteins ...
Receptor-mediated targeted drug delivery to the macrophages by using nanoparticles emerges as promising strategy to improve therapeutic efficacy of old-fashioned drug. Receptor-mediated targeted nanoparticles can migrate across the cell membrane barriers and release enclosed drug cargo at sites of infection...
Nanoparticles in the New Era of Cardiovascular Therapeutics: Challenges and Opportunities 2023, International Journal of Molecular Sciences Revitalizing myocarditis treatment through gut microbiota modulation: unveiling a promising therapeutic avenue 2023, Frontiers in Cellular and Infection Microbiology Nanomaterials...
targeted deliveryCell-membrane-coated nanoparticles have recently been studied extensively for their biological compatibility, retention of cellular properties, and... D Dehaini,X Wei,RH Fang,... - 《Advanced Materials》 被引量: 24发表: 2017年 Cell membrane-coated biomimetic nanomedicines: productive...
Not only do CMMVs serve as carriers for nanoparticles, but they also assume the functions of scavenging sponges, removing bacteria, viruses, cytokines, toxins, and chemokines via unoccupied receptors on the cell membrane. Thus, they are often called “nanodecoys” [23]. With the continuous ...
the blood and enhance accumulation of nanoparticles in the established atherosclerotic plaques for improved atherosclerosis management22. In spite of the significantly reduced RES clearance and improved payload delivery, none of these previous carriers may specifically release payload in the disease sites. ...