In the following, the method of drug loading in magnetic nanoparticles, the entry of particles into the body, targeting and drug release are discussed, and finally, a brief discussion is presented regarding the pharmacokinetics of drugs and their toxicity in the body....
Magnetic nanoparticles (MNPs) are a special kind of nanomaterials and widely used in biomedical technology applications. Currently they are popularly customized for disease detection and treatment, particularly as drug carriers in drug targeted delivery systems, as a therapeutic in hyperthermia (treating ...
Magnetic nanoparticlesdrug delivernanoparticle designsurface functionalizationbiomedical applicationclinical trialsBackground: The study of magnetic nanoparticles (MNPs) for drug delivery has recently seen a surge of interest even though the first studies were conducted as early as in the seventies. Despite ...
Magnetic nanoparticles (MNPs) represent a subclass within the overall category of nanomaterials and are widely used in many applications, particularly in the biomedical sciences such as targeted delivery of drugs or genes, in magnetic resonance imaging, and in hyperthermia (treating tumors with heat)....
Drug targeting using magnetic nanoparticles (MNPs) under the action of an external magnetic field constitutes an important mode of drug delivery. Low cargo capacity, particularly in hydrophobic drugs, is one limitation shown by MNPs. This article describes a simple strategy to enhance the drug-loadin...
Nanoparticles can be targeted towards, and accumulate in, tumor tissue by the enhanced permeability and retention effect, if sequestration by the reticuloe... M Kuruppuarachchi,H Savoie,A Lowry,... - 《Molecular Pharmaceutics》 被引量: 81发表: 2011年 ZnO nanoparticles as drug delivery agent for...
structures, and on their applications in targeted drug delivery, enhanced magnetic resonance imaging (MRI), enzyme immobilization, hyperthermia and biosensors. ... L Zhou,J Yuan,Y Wei - 《Journal of Materials Chemistry》 被引量: 168发表: 2011年 New Forms of Superparamagnetic Nanoparticles for Biom...
Further, sustained release of drugs from the nanovehicles help in long term effect of the drug along with reduction of side effects caused due to administration of high doses of drugs during cancer chemotherapy. In this scenario, magnetic nanoparticles (MNPs) have been proved to be efficient ...
These nanoparticles are likely to be used as targeted carriers to deliver platinum anticancer drugs. 展开 关键词: Manganese oxide X-ray diffraction Isothermal magnetization Magnetocaloric effect DOI: 10.1039/c1jm11369k 被引量: 48 年份: 2011
However, the derived hollow nanoparticles often have a simple microstructure and function that cannot be manipulated controllably. In addition, the potential value of these materials in the enrichment and assay of exosomes and related analytical and biomedical applications has not yet been studied37,38...