Next-Generation Sequencing Long-Read Sequencing Microarray Technology Sequencing Method Explorer All Technologies Next-generation sequencing for beginners Curious about using NGS in your research? Learn the basics of next-generation sequencing and find tips for getting started. Learn about NGS Illumina ...
第一个完整的人类基因组完成测序,完成这项工作最重要的技术之一就是长读长测序,这是产生端粒到端粒(Telomere-to-Telomere,T2T)数据的主要测序技术。而这知识long-read sequencing的一个例子,基于重大的方法层面进步以及广泛的应用领域,《nature method》选择long-read sequencing作为2022年度方法。
作为“更亲和”的测序技术，长读长测序也正在不断为方法开发和生物学研究开辟新的领域，例如机器学习等前沿技术正日益成为长读长测序数据分析工具箱的核心要素。齐碳科技是国内首家自主研发出纳米孔基因测序仪并率先开启商业化的企业，目前已有上百家机构用户使用齐碳QNome测序平台，涵盖国内领先的科研院所、高校、医院...
Nature Methods 2022年年度最佳技术——long-read sequencing 2022年2月,国际顶级期刊Nature发布了【2022年度值得关注的七大顶尖生物技术榜单】,并评述这七大顶尖生物技术有望在本年对科学研究产生重大影响,长读长测序技术赫然在榜。 4月,人类基因组测序便迎来第18座里程碑——迄今最完整的人类基因组图谱发布!其中,长...
Sentieon | 每周文献-Long Read Sequencing(长读长测序)-第七期,研究者通过将PacBio长读长数据进行组装后对基因组进行repeat和gene注释。然后,利用测序或者从公开发表文献中下载的棉花基因组数据进行比对、变异检测、联合基因分型对亚洲栽培棉和非洲亚种进行比较。此过
The viral genomes express a highly complex pattern of transcriptional overlaps, the function of which continues to remain unknown. Long-read sequencing (LRS) has become increasingly popular due to its strengths inde novoassembly and in resolving complex DNA regions as well as in determining full-le...
长读测序(Long-Read Sequencing,LRS),即第三代DNA测序技术,可以绘制更加完整的人类基因组图谱。下一代DNA测序是基因组革命背后的驱动力。虽然短读测序(Short-Read Sequencing,SRS)在过去占主导地位,但ARK认为,长读测序将迅速获取市场份额。 ARK认为,与短读测序相比,长读测序技术可以提供更高的准确性、更全面的变体...
Sentieon | 每周文献-Long Read Sequencing-第十八期 长读长测序系列文章-1 标题(英文):Chromosome-Level Genome Assembly of the Green Peafowl (Pavo muticus) 标题(中文):绿孔雀(Pavo muticus)的染色体级基因组组装 发表期刊:Genome Biology and Evolution...
PacBio incorporated the NVIDIA A100 Tensor Core GPU into its Revio system to accelerate the speed and accuracy of long‑read sequencing, while minimizing costs.
Shotgun DNA sequencing has been used to build contiguous sequence information of entire chromosomes1. However, previous sequencing reads were too short to resolve the order of repetitive sequences, because the repeats were longer than an individual read, or sequence variations between two tandem copie...