Long-Read Sequencing Microarray Technology Sequencing Method Explorer All Technologies Next-generation sequencing for beginners Curious about using NGS in your research? Learn the basics of next-generation sequencing and find tips for getting started. Learn about NGS Illumina Research & Innovation Geno...
Long-read sequencing technologies can enable the resolution of structurally complex or repetitive genome regions that are difficult or impossible to resolve with short-read sequencing. Pairing the power of long-read sequencing platforms with targeted hybridization capture technology allows researchers to effi...
Long-read sequencingPacBioOxford Nanopore TechnologyShort-read sequencingInfectious diseaseCancer genomicsStructural variantsThe extensive applications of next-generation sequencing (NGS) technologies have transformed the field of genetics and genomics research over time. In recent years, different long-read ...
作为“更亲和”的测序技术，长读长测序也正在不断为方法开发和生物学研究开辟新的领域，例如机器学习等前沿技术正日益成为长读长测序数据分析工具箱的核心要素。齐碳科技是国内首家自主研发出纳米孔基因测序仪并率先开启商业化的企业，目前已有上百家机构用户使用齐碳QNome测序平台，涵盖国内领先的科研院所、高校、医院...
第一个完整的人类基因组完成测序,完成这项工作最重要的技术之一就是长读长测序,这是产生端粒到端粒(Telomere-to-Telomere,T2T)数据的主要测序技术。而这知识long-read sequencing的一个例子,基于重大的方法层面进步以及广泛的应用领域,《nature method》选择long-read sequencing作为2022年度方法。
The Workhorse in NGS Labs: Short-Read Sequencing Short-read sequencing is a powerful tool for generating genomic data. With short read sequencing, DNA or RNA can be sequenced in a shorter amount of time and at a lower cost than traditional methods. This technology has revolutionized biomedical ...
2023年1月12号,NatureMethod报道2022年最值得关注的方法——长读段测序(Long-read sequencing)。 今年6月,Nature Method上发表关于一篇T2T的文章,并强调端粒到端粒(T2T)联盟成功地提出了第一个完整的人类基因组。这一成就是通过广泛的实验和计算努力取得的。其中,长读测序是负责生成T2T数据的主要测序技术,可以说为...
在2016年,首届瓶中基因组(GIAB)-precisionFDA真相挑战赛正式启幕,挑战参赛者从两个GIAB样本的短读长数据中识别出小变体。虽然HG001(也被称为NA12878)的基准测试数据已提前公布,但当时并未公开HG002的基准测试数据,这使得该挑战成为首个盲法种系变异检测挑战。其结果公开后,已被用作评估新变异检测方法的基准。尽管目...
2022年2月,国际顶级期刊Nature发布了【2022年度值得关注的七大顶尖生物技术榜单】,并评述这七大顶尖生物技术有望在本年对科学研究产生重大影响,长读长测序技术赫然在榜。 4月,人类基因组测序便迎来第18座里程碑——迄今最完整的人类基因组图谱发布!其中,长读长测序正是负责端粒到端粒数据的主要测序技术,以其长读长...
(HPV) DNA into the human genome is considered as a key event in cervical carcinogenesis. Here, we perform comprehensive characterization of large-range virus-human integration events in 16 HPV16-positive cervical tumors using the Nanopore long-read sequencing technology. Four distinct integration types...