Gene loci are labeled by the gene name and corresponding Entrez geneID. A chromosome locus may contain more than one gene. Therefore IIDB allows multiple labels to be associated with a single locus. Locus coordinates were used to search the ENSEMBL database for repeats, CpG islands, and ...
The immune system is a sophisticated network of different cell types performing complex biocomputation at single-cell and consortium levels. The ability to reprogram such an interconnected multicellular system holds enormous promise in treating various d
Lung cancer continues to be the leading cause of cancer death worldwide. Approximately 20% of patients with non-small cell lung cancer (NSCLC) are diagnosed with stage IIIA (N2) disease with poor outcomes [1], and neoadjuvant chemotherapy has been recommended to shrink the tumors [2]. Howeve...
The neurotransmitter-related genes are labeled. (D) Rat SrG-CG cFos gene expression with and without intraperitoneal injection of LPS (0.5 mg/kg and 1 mg/kg) (n = 7). (E) The trace of Ca2+ dynamics in SrG-CG neurons recorded by live-cell imaging. (F) Cultured SrG-CG neurons ...
(Figures S1C–S1E). 64 cell clusters were derived, covering diverse cell types in the respiratory system and peripheral blood (Figure 1B). Such an information-rich resource (available athttp://covid19.cancer-pku.cn/for quick browsing) enabled accurate annotation and analysis of these cell ...
Briefly, phagocytosis was assessed in heparin-treated whole blood incubated for 10 minutes at 4 °C (control: no phagocytosis) or 37 °C (test) with FITC-labeled E. coli. Phagocytosis was halted by the addition of cold PBS, whereas cell surface-bound FITC was quenched by addition of 1% ...
(FigureS4).bDiagram summarizes interplay between main represented pathways on the selected components.c-fSelected edges from the components plotted against time. Significant windows colored in blue, non-significant colored in grey. Resulting overall consecutive windows are labeled in blue dashed ...
More importantly, the preparation methods might meet the request of industrialization, thereby increasing the potential for the clinical development of nanovesicles-based drug delivery system. The nanovesicles of exosome-mimic from M1 macrophages could be utilized to load ferroptosis inducers against cancer...
After quality control, 54,274 cells were labeled to show their distribution (Fig. 10f). Enrichment analysis suggested that the T-cell content in tumors was significantly higher compared to normal tissues (Fig. 10g). Furthermore, the T-cell subpopulations were divided into gamma delta, CD4+, ...
A method and system for providing a virus-immune, rule-base, cross-platform software system is disclosed. The system can be configured provide industry-specific and user-specific fu