The human immune system is composed of a distributed network of cells circulating throughout the body, which must dynamically form physical associations and communicate using interactions between their cell-surface proteomes1. Despite their therapeutic potential2, our map of these surface interactions rem...
The following figure is a simple structure diagram of the immune composition. We can generally see that the immunity is divided into immune organs, immune cells and immune molecules. The real immune effects are the immune c...
T-cells attacking a cancer cell.(Image credit:Andrea Danti|Shutterstock) The role of the immune system — a collection of structures and processes within the body — is to protect against disease or other potentially damaging foreign bodies. When functioning properly, the immune system identifies ...
immune system (redirected fromImmune systems) Thesaurus Medical Related to Immune systems:immune response n. The integrated body system of organs, tissues, cells, and cell products such as antibodies that differentiates self from nonself and neutralizes potentially pathogenic organisms, agents, or subst...
The main pathogenic mechanisms of AF include electrical remodeling, structural remodeling, calcium handling abnormalities and autonomic nervous system changes2. Recently, substantial evidence suggests that inflammation and its associated immune response are associated with the initiation and maintenance of AF,...
Mucosal immunityis considered the localimmune system, and the term implies regional limitation[1]. Themucosal immune systemis a complex network composed of innate cells, acquiredimmune cellsand their derivatives, which work together to protect its integrity through the cooperation of singlecell epitheliu...
2. The immune system is a collection of structures, cells, and cell products that can fight external or internal agents harmful to the body. These components and other protective factors of the body will be the topic of this chapter.3. Immunology is the study of the normal functions and ...
however, as the tumor develops from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms thatmimic peripheral immune tolerancein order to avoid tumoricidal attack. 注: Immune tolerance Immune toleranceis the state ofunresponsivenessof the immune system to substances or...
Cytotoxic cells are composed of CD8+ T cells, gamma delta T cells (Tγδ) and natural killer (NK) cells, participating in the innate immune system. The definite function of cytotoxic cells is eliminating intracellular pathogens and abnormal cells. Unlike CD8 T cells with strict major histocompat...
The cancer immunoediting hypothesis postulates a dual role of the immune system: protecting the host by eliminating tumor cells, and shaping the tumor by editing its genome. Here, we elucidate the impact of evolutionary and immune-related forces on editi