TumorHTumorKrammerTumorWileyJournal of Leukocyte BiologyIgney FH, Krammer PH (2002) Immune escape of tumors: apoptosis resistance and tumor counterattack. J Leukoc Biol 71: 907-920.F.H. Igney, P.H. Krammer, Immune escape of tumors: apoptosis resistance and tumor counterattack, J. Leukoc. ...
Kim R,E.M.a.T.K.Cancer cell immune escape and tumor progression by exploitation of anti-inflammatory and pro-inflammatory responses. Cancer Biology and Therapy . 2005Cancer cell immune escape and tumor progression by exploitation of anti-inflammatory and pro-inflammatory responses. Kim Ryungsa,Emi...
Preventing the immune escape of tumor cells by blocking inhibitory checkpoints, such as the interaction between programmed death ligand-1 (PD-L1) and programmed death-1 (PD-1) receptor, is a powerful anticancer approach. However, many patients do not respond to checkpoint blockade. Tumor PD-L1...
The immunotherapy targeting tumor immune escape mechanisms has become a critical strategy in anticancer treatment; however, the challenge of immune resistance remains significant. Autophagy, a cellular response to various stressors, involves the degradation of damaged proteins and organelles via lysosomal ...
We performed a pan-cancer characterization of GIE prevalence across six immune escape pathways in 6,319 uniformly processed tumor samples. To address the complexity of the HLA-I locus in the germline and in tumors, we developed LILAC, an open-source integrative framework. One in four tumors ...
Lang K,Entschladen F,Weidt Cet al.Tumor immune escape mecha-nisms:impact of the neuroendocrine system.Cancer Immunology Immunotherapy. 2006jIang K,Entsehladen F,Weidt C,et a1.Tmnor immune escape mecha-- nistm :impact of the neuroendocrine system[J].Cancer Immtmol Im. munother.2006,55(7)...
Oncology Investigation of immune escape paths in the tumor microenvironment UNIVERSITY OF SOUTHERN CALIFORNIA Alan Epstein ParkRyanFold changes in 113 genes were measured using RT-qPCR in B16, RENCA, and LLC tumors of syngeneic mice for mechanisms of immune escape. Fold changes were compared at Day...
Host cells can include tumor-reactive T cells capable of killing tumor cells. Howev... S Ostrand-Rosenberg,P Sinha,DW Beury,... - 《Seminars in Cancer Biology》 被引量: 520发表: 2012年 Myeloid-derived suppressor cells and tumor escape from immune surveillance Tumor progression is known to ...
2, A and B), suggesting that PPARα could increase T cell activity. To detect the effect of PPARα on tumor immune escape, PPARα gene knockout CT-26 colon cancer cell lines were implanted into immunocompetent BALB/C mice. The results showed that PPARα gene knockout promoted tumor ...
Tumor-intrinsic mechanisms of immune escape in myeloma Recent pre-clinical and clinical studies support the strategy that triggering host immunity is critical for most anti-myeloma therapies to be effective [11,12,13,14]. PIs, IMiDs, monoclonal Abs (mAbs), autologous stem cell transplantation (ASC...