immune escape 英[iˈmju:n isˈkeip] 美[ɪˈmjoon ɪˈskep] 释义 [医]免疫逃避,免疫逃逸[病原体对宿主免疫反应的逃避] 实用场景例句 全部 Objective To investigate the effect of Fas and FasL abnormal expression onimmune escapemechanism RCC....
常见的与免疫逃避(immune escape)有关之HBV a epitope突变有: G145R,D144A, P142S,Q129H,I/T126N/A及M133L… qgenelab.blogspot.com|基于6个网页 3. 免疫逃脱 进而演 化成免疫逃脱(immune escape)的变异体。 在威廉斯基(Willimsky)和布廉奇斯坦(Blankenstein)的实验中,并不 … ...
HIV-1Immune escapeEvolutionHuman leukocyte antigen (HLACytotoxic T-lymphocyte (CTLAntibodyAdaptive, and possibly innate, host immune responses represent major selective forces driving the evolution of the human immunodeficiency virus 1 (HIV-1) group M "pandemic" strain. This immune-driven...
Studies have characterized the immune escape landscape across primary tumors. However, whether late-stage metastatic tumors present differences in genetic immune escape (GIE) prevalence and dynamics remains unclear. We performed a pan-cancer characteriza
et al. Allele-specific HLA loss and immune escape in lung cancer evolution. Cell 171, 1259–1271.e1211 (2017). Article CAS Google Scholar Thielens, A., Vivier, E. & Romagné, F. NK cell MHC class I specific receptors (KIR): from biology to clinical intervention. Curr. Opin. ...
Primary escape from anti-PD-L1/PD-1 therapy may be mediated by the numerous immunosuppressive mechanisms that inhibit anticancer T-cell responses. Owing to differences in the immune contexture at baseline, the mechanisms that govern primary escape in inflamed tumors are predicted to be fundamentally ...
These immune evasion strategies can be broadly categorized as tumor-intrinsic or tumor-extrinsic, depending on whether they originate from within the tumor or from external factors in the TME [5., 6., 7.]. Tumor-extrinsic immune escape mechanisms work by creating and sustaining an ...
BMC Infectious Diseases (2020) 20:546 https://doi.org/10.1186/s12879-020-05268-0 RESEARCH ARTICLE Open Access Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region Samara Tatielle Monteiro Gomes1,2, Ednelza da Silva Graça Amoras1, Érica Ribeiro Gomes1, Maria Alice ...
Multiple myeloma is an incurable cancer characterized by the uncontrolled growth of malignant plasma cells nurtured within a permissive bone marrow microenvironment. While patients mount numerous adaptive immune responses directed against their disease,
Immune escape is a critical gateway to malignancy. The emergence of this fundamental trait of cancer represents the defeat of immune surveillance, a potent, multi-armed and essential mode of cancer suppression that may influence the ultimate clinical impact of an early stage tumor. Indeed, immune ...