immune escape 英[iˈmju:n isˈkeip] 美[ɪˈmjoon ɪˈskep] 释义 [医]免疫逃避,免疫逃逸[病原体对宿主免疫反应的逃避] 实用场景例句 全部 Objective To investigate the effect of Fas and FasL abnormal expression onimmune escapemechanism RCC....
常见的与免疫逃避(immune escape)有关之HBV a epitope突变有: G145R,D144A, P142S,Q129H,I/T126N/A及M133L… qgenelab.blogspot.com|基于6个网页 3. 免疫逃脱 进而演 化成免疫逃脱(immune escape)的变异体。 在威廉斯基(Willimsky)和布廉奇斯坦(Blankenstein)的实验中,并不 … ...
It is characterized by the lack of ability of the immune system to eliminate transformed cells prior to and after tumor development. Characteristics Several mechanisms have been proposed and tested to explain cancer immune escape. It is now evident that both the host as well as the tumor play ...
According to the immunoediting theory, immune escape is the key to tumor survival.1There are many mechanisms of tumor immune escape (TIE), including defects in tumor antigen presentation to escape recognition by the immune system, alterations in the tumor death pathways to achieve increased resistanc...
et al. Allele-specific HLA loss and immune escape in lung cancer evolution. Cell 171, 1259–1271.e1211 (2017). Article CAS Google Scholar Thielens, A., Vivier, E. & Romagné, F. NK cell MHC class I specific receptors (KIR): from biology to clinical intervention. Curr. Opin. ...
To reveal the primary cellular populations driving the Immune Escape signature in the ccRCC TME, we leveraged scRNAseq from multiple tumor regions, lymph node, normal kidney, and peripheral blood of two ICI-naïve and four ICI-treated patients [16] (n = 167,283 single cells). We ident...
肿瘤免疫逃避(Tumor immune escape):有些肿瘤细胞具有逃避免疫机制的作用,可以使免疫细胞辨认不出谁是肿瘤细胞,因此 … ebiology.life.nthu.edu.tw|基于 1 个网页 3. 癌免疫逃脱 但这招数对子宫颈癌的癌细胞起不了多大作用。这个现象,叫「癌免疫逃脱」(Tumor Immune Escape)。
Besides, inhibiting AKT/mTOR pathway significantly suppressed PD-L1 expression, tumor growth, and immune escape in p53 mutated cells. In conclusion, mutant p53 achieved its Gain-of-Function by transcriptionally inhibiting PHLPP2 and activating AKT, which suppresses immune response and advances tumor ...
Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patien... Up-regulation of PD-L1 by EGFR activation mediates the immune escape in EGFR-driven NSCLC: Implication for optional immune targeted therapy...
Some viruses may inactivate the MHC class I antigen presentation system and thus escape the attention of the cytotoxic T lymphocytes (CTL). Nevertheless, the killer cells (NK) may destroy the invader. Herpes simplex viruses may inactivate or interfere with the TAP transporters and various subunits...