Structural Basis of IL-1 Family Cytokine Signaling. Front Immunol. 2019, 10:1412. ● Xu D, Mu R, Wei X. The Roles of IL-1 Family Cytokines in the Pathogenesis of Systemic Sclerosis. Front Immunol. 2019, 10:2025 编辑于 2021-01-22 17:23...
● Fields JK, Günther S, Sundberg EJ. Structural Basis of IL-1 Family Cytokine Signaling. Front Immunol. 2019, 10:1412. ● Xu D, Mu R, Wei X. The Roles of IL-1 Family Cytokines in the Pathogenesis of Systemic Sclerosis. Front Immunol. 2019, 10:2025...
IL-1 signaling in atherosclerosis: sibling rivalry. Nat Immunol. 2013; 14:1030-1032.Sheedy FJ, Moore KJ. IL-1 signaling in atherosclerosis: sibling rivalry. Nat Immunol 2013; 14: 1030-32.Sheedy FJ,Moore KJ.IL-1 signaling in atherosclerosis:sibling rivalry[J].Nat Immunol,2013,14(10):1030...
主要参考文献: ● Fields JK, Günther S, Sundberg EJ. Structural Basis of IL-1 Family Cytokine Signaling. Front Immunol. 2019, 10:1412. ● Xu D, Mu R, Wei X. The Roles of IL-1 Family Cytokines in the Pathogenesis of Systemic Sclerosis. ...
[2]Jing Wen Chiu , Zuhairah Binte Hanafi , Lionel Chin Yong Chew , Yu Mei , Haiyan Liu IL-1α Processing, Signaling and Its Role in Cancer Progression IL-1α Processing, Signaling and Its Role in Cancer Progression [3]J. Palomo et al., The interleukin (IL)-1 cytokine family – Ba...
Zhang W et al. IL-1 Signaling in Tumor Microenvironment. Adv Exp Med Biol. 2020;1240:1-23. Bent R et al. Interleukin-1 Beta-A Friend or Foe in Malignancies? Int J Mol Sci. 2018 Jul 24;19(8):2155. Mitchell CA et al. Stromal niche inflammation mediated by IL-1 signalling is a ...
IL-1家族细胞因子通过与受体亚基结合激活细胞内信号通路,如IL-1RI/IL-1R1、IL-18Rα/IL-1R5、IL-1Rrp2/IL-1R6或ST2/IL-1R4,然后募集一个辅助受体来形成活性受体复合物。由IL-1α、IL-1β、IL-18、IL-33、IL-36α、IL-36β或IL-36γ触发的信号级联激活MAPK和NF-κB,导致促炎因子、趋化因子和炎症...
[2]Jing Wen Chiu , Zuhairah Binte Hanafi , Lionel Chin Yong Chew , Yu Mei , Haiyan LiuIL-1αProcessing, Signaling and Its Role in Cancer Progression IL-1αProcessing, Signaling and Its Role in Cancer Progression [3]J. Palomo et al., The interleukin (IL)-1 cytokine family – Balance...
IL-6 拥有三种信号通路:经典信号通路(Classic signaling)、反式信号通路(Trans-signaling)和反式呈递信号通路(Trans-presentation signaling/IL-6 cluster signaling)。 图6. IL-6 经典信号通路和反式信号通路[32]。 经典信号中,IL-6 与靶细胞(如肝细胞、单核细胞和部分 T 细胞亚群)膜上受体 IL-6R 结合(IL-...
Zhang W et al. IL-1 Signaling in Tumor Microenvironment. Adv Exp Med Biol. 2020;1240:1-23. Bent R et al. Interleukin-1 Beta-A Friend or Foe in Malignancies? Int J Mol Sci. 2018 Jul 24;19(8):2155. Mitchell CA et al. Stromal niche inflammation mediated by IL-1 signalling is a ...