We aim to determine the dose- and time-dependent effects of IL-1beta and morphine on MOR expression in SK-N-SH cells and elucidate the signaling pathway responsible for this regulation of MOR using quantitative real-time-PCR (qRT-PCR) and immunocytochemistry (ICC). A time-dependent IL-1...
A novel beta-catenin signaling pathway activated by IL-1beta leads to the onset of epi- thelial-mesenchymal transition in breast can- cer cells. Cancer Lett 2014; 354: 164-71.Perez-Yepez EA,Ayala-Sumuano JT,Lezama R,et a]. A novel {3-catenin signaling pathway activated by IL-I ...
1 production positive regulation of neutrophil chemotaxis extrinsic apoptotic signaling pathway in absence of ligand negative regulation of branching morphogenesis of a nerve negative regulation of neural precursor cell proliferation negative regulation of extrinsic apoptotic signaling pathway in a...
Further, mutation of the identified redox sensitive cysteines inhibits IL-1β signaling and NFκB activation. This research has helped to refine the understanding of the IL-1β signaling pathway, and may ultimately lead to new therapeutic targets for controlling inflammation. 展开 ...
Dendritic Cells Developmental Lineage Pathway IL-1 Family Signaling Pathways IL-21 Signaling and its Primary Biological Effects in Different Immune Cell Types IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types Show More R&D Systems Guarantee We offer a 100% guar...
Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012;21:66–81. Article PubMed Central CAS PubMed Google Scholar Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, et al. Human ...
Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta The mechanism of interleukin-1 (IL-1) signaling is unknown. Tumor necrosis factor-α uses a signal transduction pathway that involves sphingomyelin hydroly... S Mathias,A Younes,...
Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012;21:66–81. 8. Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, et al. Human mesenchymal stem cells ...
IL-1β lacks a signal sequence peptide for classical ER/Golgi pathway and is instead secreted alongside caspase-1 via an alternate and incompletely understood mechanism. IL-1β signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1α. These cytokines play ...
Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012;21:66–81. 8. Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, et al. Human mesenchymal stem cells exert potent anti...