IL-7/IL-7R signaling pathway might play a role in recurrent pregnancy losses by increasing inflammatory Th17 cells and decreasing Treg cells. American journal of reproductive immunology : AJRI 2016; 76:454-464.Wu L,Li J,Xu HL,et al.IL-7/IL-7R signaling pathway might play a role in ...
Enables cytokine activity and growth factor activity. Acts upstream of or within several processes, including negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of lymphocyte activation; and tissue homeostasis. Located in extracellular space. Is expressed ...
Signaling pathway in HEK-Blue™ IL-7 cells HEK-Blue™ IL-7 cellswere engineered from the human embryonic kidney HEK 293 cell line to detectbioactive interleukin-7(IL-7)by monitoring the activation of the JAK/STAT5 pathway. They can also be used for screening antibodies or small molecule...
to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. Diseases such as Epidermodysplasia verruciformis 5 and Epidermodysplasia Verruciformis 1 are associated with IL7. The related pathways of IL7 include PEDF Induced Signaling and IL-7 Signaling Pathway. ...
signaling pathway in absence of ligandregulation of DNA recombinationcell morphogenesisnegative regulation of T cell mediated cytotoxicityimmunoglobulin productionimmune responsesignal transductioncell surface receptor signaling pathwayregulation of cell sizepositive regulation of gene expressioncell growthT cell ...
CNY3,528.00 下单后预计有货时间 25-Apr-2025 查看价格 批量或定制请求 Application Created with Sketch. 图:1/5 Interleukin-7 (IL-7) Antibody (3574-MSM2-P0) in ICC/IF Immunofluorescence analysis of PFA-fixed U-87 cells stained using Interleukin-7 (IL-7) Mouse Monoclonal Antibody (IL7/4012)...
For example, while TFH cells can and do develop during the initial response to antigen, it has also been demonstrated that other effector T-helper cell subsets are capable of adopting a TFH-like profile, making a 'post-effector' developmental pathway plausible as well8–13. These previous ...
Stimulation of TAIL7 cells with IL-7 triggers signaling events, including the activation of the JAK/STAT pathway, hyperphosphorylation of Rb, and down-regulation of p27kip1. Importantly, specific blockade of JAK3 abrogates the proliferative and survival effects of IL-7 on TAIL7 cells. These ...
et al. Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity 21, 357–366 (2004). Article CAS PubMed Google Scholar Pinto-Sanchez, M. I. et al. Society for the Study of Celiac Disease ...
The possible significance of the IL7R gene and the IL-7 signaling pathway genes as biomarkers of aging was sug- gested by the results of a study which analyzed chroma- tin accessibility and transcriptomics of peripheral blood mononuclear cells (PBMCs) in young and older adults using systems ...