PTX treatment does not affect the autophagic activity in the human macrophage cell line THP-1.Ali, VuralTravis, J. McQuistonJoe, B. BlumerChung, ParkIlYoung, HwangYolanda, WilliamsBeyChongShan, ShiDzwokai, Zach MaJohn, H. Kehrl
These cells are derived from human leukemia monocytic THP-1 cells, a common model to study monocyte/macrophage functions, mechanisms, and signaling pathways. They express several pattern recognition receptors (PRRs) and co-adaptors, including TLR8 and UNC93B1, but not TLR7 [1-2]. Indeed, THP...
中文名称:THP-1人急性白血病单核巨噬细胞株说明书 中文同义词:THP-1人急性白血病单核巨噬细胞株说明书 英文名称:THP-1 Human Acute Leukemia Mononuclear Macrophage Cell Line Instructions 英文同义词:THP-1 Human Acute Leukemia Mononuclear Macrophage Cell Line Instructions ...
1.Expression of genes for inflammatory cytokines in human monocytic cell line THP-1 during exposure to isoflurane;目的研究异氟醚对人类单核细胞株(THP-1)细胞、白细胞介素-1β(IL-1β)、IL-8、肿瘤坏死因子-α(TNF-α)、干扰素-γ(IFN-γ)、IL-4和IL-10mRNA表达的影响。 3)monocyte line Raw264.7...
We subsequently deleted KEAP1 in THP-1 cells to validate the effect of KEAP1 on macrophage pro-inflammatory activation. We designed three sgRNAs to target the human KEAP1 (Supplementary Fig. 2a) with good efficiency (Supplementary Fig. 2b, c), and the KEAP1 level could be reduced in THP...
The human monocyte/macrophage cell line THP-1 (ATCC, Virginia, USA) and human glioblastoma cell line SF268 (ATCC) were propagated in Roswell Park Memorial Institute 1640 medium (RPMI 1640; Thermo Fisher Scientific) supplemented with 10% (v/v) fetal bovine serum (FBS; Thermo Fisher Scientific...
α7 nicotinic acetylcholine receptors (nAChRs) are ubiquitous in the nervous system and ensure important neurophysiological functionality for many processes. However, they are also found in cells of the immune system, where their role has been less studi
Corrigendum to “Leptospira interrogans infection leads to IL-1β and IL-18 secretion from a human macrophage cell line through reactive oxygen species and cathepsin B mediated-NLRP3 inflammasome activation” [Microbe Infect (2018) 254–260] Microbes and Infection, Volume 23, Issue 1, January–Feb...
Cell culture and differentiation THP-1, a human promonocytic leukemia cell line and the Raw 264.7 mouse macrophage cell line were obtained from the American Type Culture Col- lection (Massas, VA) and the Korea Cell Line Bank (Seoul, Korea), respectively. Cells were maintained in RPMI-1640 ...
The FANTOM4 study identified transcriptional start sites active during proliferation arrest and differentiation of the human monocytic cell line THP-1. Systematic knockdown of 52 transcription factors provide support for their model in which a complex tr