The ability of flavonoids to attenuate macrophage pro-inflammatory activity and to promote macrophage-mediated resolution of inflammation is still poorly understood at the biochemical level. In this study, we have employed NMR metabolomics to assess how therapeutically promising flavonoids (quercetin, naring...
10X Genomics Loupe Cell Browser package was used to visualize the cell clustering. An output file (.cloupe) from CellRnager was used as an input for 10X Genomics Loupe Cell Browser package. The .cloupe file contained the expression data for all cells, a t-distribution stochastic neighbor emb...
Experiments with murine microglia and human microglial cell lines56,57 recapitulate key hallmarks of previous macrophage studies, such as the upregulation of glycolysis activity. Indeed, we observed an overall promotion of glycolysis, coupled to mitochondrial dysfunction in mouse microglia, supported by ...
In support of NF-κB involvement, we observed that thrombin induced IκB phosphorylation in THP-1 macrophages, an effect that has already been reported in a murine macrophage cell line [14]. IκB may be phosphorylated by IκB kinase, which is activated in turn by a number of kinases, ...
Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway. Cell Death Differ. 2019;27(6):1765. Article PubMed CAS PubMed Central Google Scholar Komander D, Clague MJ, Urbe S. Breaking the chains: structure and function of the de...
;SOLUTION: This cell-line CMC-1 (FERM P-15071) is obtained by collecting bone mallow cells of an acute myelocytic leukemia patient and subculturing the same in a RPMI-1640 medium containing granulocyte-macrophage colony stimulating factor (GM-CSF) and 20% fetal bovine serum (FBS) at 37°C...
fraction (5−10%) of the hPGCLC-derived cells (Fig.1c,eand Extended Data Fig.4e,f,o,p). Thus, BMP signalling reproducibly promotes hPGCLC differentiation from four independent human iPS cell lines, although their propagation and differentiation dynamics show line-dependent heterogeneity....
J774.2 cells are a murine macrophage cell line. View article Review article Eighteen‑carbon trans fatty acids and inflammation in the context of atherosclerosis Progress in Lipid Research Journal2019, Progress in Lipid Research Carina A. Valenzuela, ... Philip C. Calder 7.3 Studies in...
Rat macrophage inflammatory protein 5 (MIP-5) ELISA Kit 大鼠巨噬细胞蛋白5(MIP-5)ELISA试剂盒 HumanIschemiaModifiedAlbumin,IMAELISAKit 人缺血修饰白蛋白(IMA)ELISA试剂盒 96T/48T 进口分装 HumanAlpha-Actin,αActinELISA试剂盒人α肌动蛋白(αActin)ELISA试剂盒规格:96T/48T 植物β-淀粉酶(β-AMYLASE)活性...
granulocyte-macrophage progenitor; EoBP: eosinophil-basophil progenitor; MEP: megakaryocytic-erythroid progenitor.(B)Representative analyses of the cell surface marker expression on HUVEC 1 (black histograms) in comparison to isotype-controls (white histogram). Numbers indicate the mean fluorescence intensity...