Finally, apoptosis, phagocytosis, and cell migration assays were performed to investigate the effects of the extract on macrophage functions. The obtained results illustrated that I. coerulea extract possesses anti-oxidant and anti-inflammatory activities. In addition, current study reported that I. ...
中文名称: THP-1人急性白血病单核巨噬细胞株说明书 中文同义词: THP-1人急性白血病单核巨噬细胞株说明书 英文名称: THP-1 Human Acute Leukemia Mononuclear Macrophage Cell Line Instructions 英文同义词: THP-1 Human Acute Leukemia Mononuclear Macrophage Cell Line Instructions CAS号: 分子式: 分子量: 0...
1h, i). This demonstrated that the validity of our screen in THP-1 cells was credible. We subsequently deleted KEAP1 in THP-1 cells to validate the effect of KEAP1 on macrophage pro-inflammatory activation. We designed three sgRNAs to target the human KEAP1 (Supplementary Fig. 2a) with ...
α7 nicotinic acetylcholine receptors (nAChRs) are ubiquitous in the nervous system and ensure important neurophysiological functionality for many processes. However, they are also found in cells of the immune system, where their role has been less studi
Corrigendum to “Leptospira interrogans infection leads to IL-1β and IL-18 secretion from a human macrophage cell line through reactive oxygen species and cathepsin B mediated-NLRP3 inflammasome activation” [Microbe Infect (2018) 254–260] Microbes and Infection, Volume 23, Issue 1, January–Feb...
These cells are derived from human leukemia monocytic THP-1 cells, a common model to study monocyte/macrophage functions, mechanisms, and signaling pathways. They express several pattern recognition receptors (PRRs) and co-adaptors, including TLR8 and UNC93B1, but not TLR7 [1-2]. Indeed, THP...
human monocytic cell line人类单核细胞株 1.Expression of genes for inflammatory cytokines in human monocytic cell line THP-1 during exposure to isoflurane;目的研究异氟醚对人类单核细胞株(THP-1)细胞、白细胞介素-1β(IL-1β)、IL-8、肿瘤坏死因子-α(TNF-α)、干扰素-γ(IFN-γ)、IL-4和IL-10...
In differentiated human THP-1 macrophages, TCDD increased both TNF-α mRNA expression and secretion of TNF-α protein in the absence of LPS. In contrast, in a murine macrophage cell line, Raw 264.7, TNF-α could only be induced by TCDD in the presence of LPS (Figure 1D). The requi- ...
(b) Flow-cytometry assessment of cell surface antigens induced upon monocyte to macrophage differentiation. Each histogram represents cell surface expression on THP-1 cells (thick grey line), PMA differentiated THP-1 cells (thin black lines) and THP-1 co-cultured with MSCs (thick black line)....
4) THP-1 macrophage THP-1巨噬细胞 1. In order to study the effects of LDL and oxLDL on expression of PCSK9 and LDLR in THP-1 macrophages and find the relationship between them. 分别用0mg/L、10mg/L、20mg/L、30mg/L的LDL和0mg/L、10mg/L、20mg/L、30mg/L的oxLDL处理THP-1巨噬...