[2] Serena T , Federica D M , Jieun K , et al. Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?[J]. Frontiers in Pharmacology, 2018, 9:71-. [3,4] 王庸晋, 王治平, 石变...
关键词:THP-1;M1型巨噬细胞;食管鳞癌细胞Eca109;共培养Effects of THP-1-derived M1 macrophages on apoptosis, proliferationand migration of esophageal squamous cell carcinoma cellsYANG Yinyin 1 , LI Huiwu 2 , LIU Ling 1 , ZHU Shimao 1 , HAINISAYIMU Tuersun 1 , LI Hui 3 *( 1 School of ...
THP-1 derived macrophagesarsenitearsenic toleranceABCA1intracellular arsenicOrlistat is an FDA-approved over-the-counter drug to treat obesity through the inhibition of lipase activity. Macrophages, which express high levels of lipoprotein lipase (LPL), are important phagocytes in the innate immune ...
ConclusionsAt early stage of infection, HCMV can stimulate autophagy in THP-1 derived macrophages, which may not depend on the replication of HCMV. At the late phase of infection, the inhibition of autophagy in THP-1 derived macrophages may be related to the factors such as viral replication...
1. Marie Genin, Francois Clement, Antoine Fattaccioli, etc. M1 and M2 macrophages derived from ...
oxLDL on the PPARδexpression in THP-1 derived macrophage and observed the effect of PPARδagonist GW501516 on macrophage proliferation, apoptosis and foam cells formation. 7 Part I. Effect of oxLDL on PPARδExpressionInduced by oxLDL in THP-1 Derived Macrophages Objective:To identify the effec...
The protein expression of IL-1β in HCMV infected group was significantly higher than the mock-infected control group and poly (dA : dT) control group at 6 hours after HCMV infected THP-1 derived macrophages, while no significant difference between the LPS + ATP control group. ConclusionsThe...
THP-1-derived macrophages were sonicated with the ultrasonic processor (Sonics, Newtown, USA) on ice to quantify the target proteins. Isopropanol (1 mg/ml cholesterol) was added to dissolve cholesterol and reserved at 20°C. Thereafter, 0.4 U cholesterol oxidase (Solarbio) in 100 μl 0.5% ...
THP-1-derived macrophages. The results revealed the great up-regulations of M2 markers CD206 and CD163 and the down-regulation of M1 marker CCR7. ELISA analysis showed that the release of IL-1b, IL-10 and TNF- was all up-regulated. This study indicated that the tumor cell 40 ...
Comparative transcriptomic analysis of THP- 1- derived macrophages infected withMycobacterium tuberculosisH37Rv, H37Ra and BCG Pu W,Zhao C,Wazir J,Su Z,Niu M,Song S,Wei L,Li L,Zhang X,Shi X, Wang H. J Cell Mo...