Stone, Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism, Free Radic. Res. 25 (1996) 181^192.Graham A, Wood JL, O'Leary VJ, Stone D. Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism. Free Radic Res 1994;21:295 A/308....
Supplementation of THP-1 cultures with cAMP to stimulate hormone-sensitive lipase did not significantly enhance net hydrolysis of EC or cholesterol efflux. In conclusion, human THP-1 macrophages contain a large and metabolically active pool of triglyceride and a relatively inactive pool of EC. The ...
4.Dilazep influence acetylated low density lipoprotein uptake through down-regulation of scavenger receptor expression in THP-1 derived macrophages地拉卓对人类单核细胞株源性巨噬细胞摄取乙酰化低密度脂蛋白的影响 5.The Screening of Listeria Monocytogenes Mutants on Biofilm Formation;单核细胞增生李斯特菌菌膜...
We have recently profiled the 3D organization and long-range interactome of human THP-1 monocytes and THP-1-derived macrophages through deeply sequenced in situ Hi-C experiments. High-resolution mapping of DNA loops identified both static and dynamic loop-based regulation of key macrophage genes du...
25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages. 来自 国家科技图书文献中心 喜欢 0 阅读量: 81 作者:L Xu,S Shen,Y Ma,JK Kim,RodriguezAgudo, Daniel,DM Heuman,PB Hylemon,WM Pandak,S Ren ...
We present two functions of human IFI16 in the cGAS-STING pathway. Using human phorbol myristate acetate (PMA) treated THP1 cells and human monocyte-derived macrophages (MDMs) depleted of IFI16, we find that early interferon expression in the response to viral infections or DNA transfection requ...
Figure 1 (A) Schematic representation of unstimulated (M0 controls) and pro-inflammatory (M1) THP-1-derived macrophages; (B) Typical 1H NMR spectrum obtained for polar extracts of THP-1-derived macrophages; (C) Multivariate analysis of spectral data from M0 and M1 macrophages; D) Heatmap of...
January2015Keywords:MycobacteriumabscessusHO-1THP-1cellsOxidativestressabstractMycobacteriumabscessus(M.abs)isarapidlygrowingmycobacterialspeciesthatinfectsmacrophages,andisanimportantpathogeninpatientswithcysticfibrosis.WestudiedtheearlystagesofM.absin-fectionofmacrophages,withemphasisontheroleofheme-oxygenase-1(HO-1...
1a) and THP-1-derived macrophages (tMAC) could be further activated towards pro-inflammatory macrophages after LPS and IFN-γ stimulation (Supplementary Fig. 1b). No significant differences in the pro-inflammatory activation capacity were found between WT and the sgRNA library virus transduced THP...
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