Stimulation of human macrophages (THP-1) using toll-like receptor-2 (TLR-2) agonist decorated nanocarriers. J Drug Target 2009;17:662e70.Heuking, S.; Adam-Malpel, S.; Sublet, E.; Iannitelli, A.; Stefano, A.D.; Borchard, G. Stimulation of human macrophages (THP-1) using Toll-...
Stimulation of interleu- kin-8 production in human THP-1 macrophages by apolipoprotein(a). Evidence for a critical involvement of ele- ments in its C-terminal domain. J Biol Chem. 2001;276:46864-9.Klezovitch O, Edelstein C, Scanu AM. Stimulation of interleukin-8 pro- duction in human ...
spiralis can affect the polarization of human THP-1 macrophages. Co-culture of adult parasite stage and cells in direct contact without LPS addition had a significant impact on TNFα levels. Interestingly, in settings with the addition of LPS, the levels of IL-1β and TNFα significantly ...
Although THP-1 macrophages accumulated FC and esterified cholesterol (EC), assessed by both mass and radioactivity, cellular EC always demonstrated a much lower specific activity (cpm/ microg) than did cellular FC, and several potential causes of this finding were investigated. Inhibition of acyl-...
The present study has investigated the effects of StAR in the apoptotic process of human THP-1 derived macrophages induced by serum withdrawal or Ox-LDL. Overexpression of StAR significantly decreased the number of apoptotic macrophages by decreasing the expression of pro-apoptotic genes Caspase-3 ...
THP1-Dual™ hTLR3 cells derive from THP-1 monocytes and overexpress the human TLR3 gene as well as all elements important in its signaling cascade. They also feature two inducible reporter genes, allowing the concomitant study of the IRF and NF-κB pat
TLR7 is mainly found in plasmacytoid dendritic cells (pDCs) and B cells, whereas TLR8 is highly expressed in monocytes, monocyte-derived DCs (mDCs), and macrophages [3]. TLR7 and TLR8 trafficking and signaling Upon viral infection, the chaperone protein UNC93B1 interacts with TLR7 and ...
Collectively, 1m increases ABCA1 expression in human THP-1 macrophages. The mechanisms involve the activation of the LXRα-ABCA1 pathway and suppression of certain microRNAs that regulate ABCA1 expression. 展开 关键词: atherosclerosis, cholesterol efflux, ATP-binding cassette transporters A1, chalcone ...
1.Expression of genes for inflammatory cytokines in human monocytic cell line THP-1 during exposure to isoflurane;目的研究异氟醚对人类单核细胞株(THP-1)细胞、白细胞介素-1β(IL-1β)、IL-8、肿瘤坏死因子-α(TNF-α)、干扰素-γ(IFN-γ)、IL-4和IL-10mRNA表达的影响。 3)monocyte line Raw264.7...
In HIV-1Bal-infected macrophages, Lipofectamine (up to 8 μM) and Lipofectin (up to 40 μM) were not toxic after a 4-h treatment, while DMRIE reagent at 40 μM was toxic. While a 4-h treatment of THP-1 /HIV-1 IIIB cells with the cationic liposomes was not toxic, even up to ...