Stone, "Human (THP-1) macrophages oxidize LDL by a thiol-dependent mech- anism," Free Radical Research, vol. 25, no. 2, pp. 181-192, 1994.Graham, A., Wood, J. L., O'leary, V. J. & Stone, D. Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism. Free ...
4) THP-1 macrophage THP-1巨噬细胞 1. In order to study the effects of LDL and oxLDL on expression of PCSK9 and LDLR in THP-1 macrophages and find the relationship between them. 分别用0mg/L、10mg/L、20mg/L、30mg/L的LDL和0mg/L、10mg/L、20mg/L、30mg/L的oxLDL处理THP-1巨噬...
Although THP-1 macrophages accumulated FC and esterified cholesterol (EC), assessed by both mass and radioactivity, cellular EC always demonstrated a much lower specific activity (cpm/ microg) than did cellular FC, and several potential causes of this finding were investigated. Inhibition of acyl-...
Stimulation of interleukin-8 production in human THP-1 macrophages by apolipoprotein(a). Evidence for a critical involvement of elements in its C-terminal domain. Journal of Biological Chemistry 276, 46864-46869, 2001.Klezovitch O,Edelstein C,Scanu AM.Stimulation of interleukin-8 production in ...
There has been a lack of research on CYP4 in macrophages, but fatty acid accumulation and lipid trafficking in macrophages have been suggested to be a main cause of atherosclerosis. All human CYP4 genes (n=12) were screened in THP1 macrophages by gene-specific reverse transcriptase-polymerase ...
We have recently profiled the 3D organization and long-range interactome of human THP-1 monocytes and THP-1-derived macrophages through deeply sequenced in situ Hi-C experiments. High-resolution mapping of DNA loops identified both static and dynamic loop-based regulation of key macrophage genes du...
Reduction of transition metals by human (THP-1) monocytes is enhanced by activators of protein kinase Catherogenesismonocyteoxidized low-density lipoproteinprotein kinase Ctransition metalsthiolsMacrophages oxidize low-density lipoprotein (LDL) by enzymatic and non-enzymatic mechanisms; however, it is ...
5) monocyte-macrophages 单核-巨噬细胞 1. Comparison of the characteristic of T-cell-stimulation between dendritic-like cells induced from monocyte-macrophages derived from placental tissue in different gestational ages 妊娠不同时期胎盘单核-巨噬细胞来源的树突样细胞刺激T细胞作用的比较 2. Objective:...
Very-low-density lipoprotein alters the secretion of apolipoprotein E-containing lipoprotein particles from human (THP1) macrophages... EM Lindholm,A Graham - 《Atherosclerosis》 被引量: 7发表: 1999年 Acquisition of Secretion of Transforming Growth Factor-β1 Leads to Autonomous Suppression of Scaveng...
1.Expression of genes for inflammatory cytokines in human monocytic cell line THP-1 during exposure to isoflurane;目的研究异氟醚对人类单核细胞株(THP-1)细胞、白细胞介素-1β(IL-1β)、IL-8、肿瘤坏死因子-α(TNF-α)、干扰素-γ(IFN-γ)、IL-4和IL-10mRNA表达的影响。 3)monocyte line Raw264.7...