process is regulated by theX-Inactive-Specific Transcript(XIST), encoding for a long non-coding RNA, exclusively expressed from the inactive X chromosome (Xi). XIST interacts with various RNA binding proteins and chromatin modifiers to form a ribonucleoprotein (RNP) complex responsible for the trans...
Overall, our genome data analyses from both organisms show frame 1 is more likely to harbour asORFs, than the other two frames. Antisense overlap can facilitate ORF emergence and reduce ORF loss We next analysed how likely it is for asORFs to emerge, when they are not already present. To...
FFPE samples are archived in “biobanks” developed by universities and hospitals or created for commercial purposes by companies serving the research community and are therefore often referred to as “biobank samples”. FFPE samples present a unique window into the past for scientific exploration. ...
Plant architecture is a significant set of agronomic traits that determine rice yield, mainly influenced by factors including tillering and plant height (Wang and Li2005). The DEAD-box RNA helicase TOGR1, located in the nucleus, is regulated by both temperature and circadian clock, can serve as...
With the intensification of the greenhouse effect, a series of natural phenomena, such as global warming, are gradually recognized; when the ambient temperature increases to the extent that it causes heat stress in plants, agricultural production will in
In plants, the LCM technique coupled with high-throughput gene expression profiling is a powerful tool widely used to identify a variety of molecular mechanisms related to vascular tissue [13,14,24,25]. However, it can present challenges in obtaining high-quality RNA for transcriptomic analysis. ...
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Genes interpreted with a bias were mostly those present at lower concentration. Also, the number of isoforms and exons per gene were determinants. Previous pipeline versions using featureCounts showed a higher sensitivity to detect one-isoform genes like ERCC. To ensure data ...
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et al. Lack of ability to present antigens on major histocompatibility complex class II molecules aggravates atherosclerosis in ApoE−/− mice. Circulation 139, 2554–2566 (2019). Article CAS PubMed Google Scholar Bonacina, F. et al. Myeloid apolipoprotein E controls dendritic cell antigen ...