Protein coding features can emerge de novo in non coding transcripts, resulting in emergence of new protein coding genes. Studies across many species show that a large fraction of evolutionarily novel non-coding RNAs have an antisense overlap with protei
if there is some rules to identify flexible amino acids, and what's the best program to ...
Let's focus on immunity first, which is the ability of the immune system to fight against pathogens. If immunity is like an army, while the virus is the enemy force. When the enemy (germ) wants to invade us, the ...
The present invention relates to a method for identifying a compound of peptides and other high affinity and blocked with specific signaling mediated by G protein-coupled receptor. Test to be developed in conjunction with these methods are also disclosed. [Selection] Figure Figure 1ギルクリスト,...
Having confirmed a series of pertinent observations, we then attempted to use the overlap metric Δ to identify new trends in this chemical space. The most striking observation concerns the heterogeneity of the PPI targets. Indeed, a rapid overlook of all of the individual PPI targets from both...
Introduction: The N-terminus of a protein can encode several protein features, including its half-live and its localization. As the proteomics field remains dominated by bottom-up approaches and as N-terminal peptides only account for a fraction of all analyzable peptides, there is a need for...
Generative AI is an artificial intelligence (AI) that can produce content such as audio, text, code, video, images, and other data. While previous AI algorithms were used to identify patterns within a training data set and make predictions, generative AI uses machine learning algorithms to creat...
It is commonly assumed that a heterotrophic ancestor of the supergroup Archaeplastida/Plantae engulfed a cyanobacterium that was transformed into a primary plastid; however, it is still unclear how nuclear-encoded proteins initially were imported into th
These are biologically important questions because the answer to the first two questions could impact our understanding of how protein homeostasis is maintained in cells. The answer to the final question would help to explain how synonymous mutations can have long term impacts on protein structure and...
The first paper to link topo III and RecQ function. Article CAS PubMed Google Scholar DiGate, R. J. & Marians, K. J. Identification of a potent decatenating enzyme from Escherichia coli. J. Biol. Chem. 263, 13366–13373 (1988). The first study to identify a decatenase activity ...