Analyze protein structures, perform structural alignments, and prepare structures for publication Analyze biophysical properties to make predictions about protein function Enhance experimental protein structure data or predict structures from sequence data with NovaFold protein modeling Integrate NGS data with pr...
How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations: The P-Type ATPase Example In the past 15 years, a large body of structural information on P-type ATPases has accumulated in the Protein Data Bank. The available crystal structures cover different enzymes in...
Tryptophan fluorescence is a powerful tool for studying protein structure and function, especially membrane-active proteins and peptides. It is arguably the most frequently used tool for examining the interactions of proteins and peptides with vesicular unilamellar model membranes. However, high light ...
Description of local protein structures have hence focused on the elaboration of complete sets of small prototypes or "structural alphabets", able to analyze local protein structures and to approximate every part of the protein backbone [1]. The principle of a structural alphabet is simple (see ...
“The most reliable approach to localize a post-translational modification in the primary structure of a protein or peptide is the recording of tandem MS spectra,” says Albert Sickmann, group leader of the Protein Mass Spectrometry & Functional Proteomics Group at the University of Würzburg. “...
AI is also proving invaluable to medical researchers trying to find a vaccine for the COVID-19 virus. Among other things, they are using AI to search thousands of research papers, and to analyze the protein structure of the virus in order to find the right components for a vaccine.In...
Using protein structure databases likeUniprotand interactive modeling sites likeProtein Model Portal, we can punch in the alanine variant at position 112 and see where it lies among the various loops and folds of the protein. The main article image at top shows the whole ATP6 protein and the ...
These are biologically important questions because the answer to the first two questions could impact our understanding of how protein homeostasis is maintained in cells. The answer to the final question would help to explain how synonymous mutations can have long term impacts on protein structure and...
Swiss-PdbViewer is a dedicated free PDB file viewer for Windows 11/10. It lets you visualize and analyze multiple protein structures at a time. You can analyze protein structure, DNA structure, etc., contained in a PDB file. Besides the PDB file, it also lets you open and view MOL and...
Three genes were identified to encode Ca+2 calmodulin protein, CALM1, CALM2, and CALM3 and each has specificity for transcription activity indifferent tissues. [95]. A study to analyze the expression levels of different types in GBM found that, CALM1,and CALM2 are significantly expressed more...