Here, we introduce the protein structure idealization problem. We focus on the protein backbone structure idealization. We describe a fast O(nm/??) dynamic programming algorithm to find an idealized protein bac
2. Spontaneous protein folding 2.1. Protein folding kinetics in vivo and in vitro: basic experimental facts In vivo, protein biosynthesis takes minutes (comparable to the whole life cycle of a bacterium, which can take only about 20 min), and the formation of the properly folded structure of ...
ribosome (protein synthes Identify the organelle from the given description or function: The highly active region of the nucleus that is required for the synthesis of ribosome. Describe the chemical structure of proteins and their importance to cells....
The very first of the thousand steps, if you want to find something new, is to learn to live with uncertainty, and to learn to accept failure as the norm, because looking for the unknown is like being a trapeze...
Like other species, we are the products of millions of years of adaptation. Now we're taking matters into our own hands.
“The most reliable approach to localize a post-translational modification in the primary structure of a protein or peptide is the recording of tandem MS spectra,” says Albert Sickmann, group leader of the Protein Mass Spectrometry & Functional Proteomics Group at the University of Würzburg. “...
How Much Protein Do You Need? Intake Guidelines Proteins are the basic building blocks of the human body. They are made up ofamino acidsand are needed for the structure and function of muscles, blood, skin, hair, nails, and internal organs. Next to water, protein is the most abundant sub...
Recent studies have advanced our understanding of gene classes that tend to undergo duplication, and how natural selection acts on them. The co-option of pre-existing, secondary protein functions is emerging as a widespread feature in the evolution of ge
Protein-protein interactions (PPIs) play vital roles in life and provide new opportunities for therapeutic interventions. In this large data analysis, 3,300 inhibitors of PPIs (iPPIs) were compared to 17 reference datasets of collectively ~566,000 compounds (including natural compounds, existing drug...
How to make proteins soluble if you find that the protein of your interest is in pellet rather than being in the supernatant?SolubilitySolubility is a property of a given molecule that generally depends on the ability of a certain molecule ...