443种HIF-1信号通路化合物的集合,可用于细胞氧感知相关研究。 规格 预溶于DMSO或水 100uL/well 询价获取超大折扣 全国免费电话:400-668-6834 | Email:info@selleck.cn 您可以选择: 特定分子选择 规格 分子所置板上位置 粉末或DMSO溶液 客户使用该化合物库发表的文献286篇: ...
These processes could alter mitochondrial morphology, number, as well as distribution, to regulate complicated cellular signaling processes like metabolism. Meanwhile, they also could modulate cell proliferation and apoptosis. The initiation and progression of several diseases, such as tumors, NDs, ...
骨生物学进展:病理性HIF1α信号驱动脂肪前体细胞功能障碍 Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity 作者:MengleShao,Chelsea Hepler,Qianbin Zhang, Bo Shan, Lavanya Vishvanath, Gervaise H.Henry, Shangang...
ScienCell's GeneQuery™ Human HIF1 Signaling Response qPCR Array Kit (GQH-HFT) is designed to facilitate gene expression profiling of 88 key genes involved in HIF1 downstream signaling upon hypoxia-induced activation. HIF1 activity is a major component of the human response to hypoxia. Brief ...
signaling. HIF-1 exerts pleiotropic effects on both cancer and stromal cells. For example, HIF-α-dependent expression of VEGF-A and PDGF-B induces angiogenesis by promoting proliferation and migration of pericytes, endothelial and vascular smooth muscle cells. In cancer-associated fibroblasts (CAFs)...
结果表明黄芪、丹参、三七共有9个共同通路(P<0.05),见图3,其中HIF-1 signaling pathway、PI3K-Akt signaling pathway、ras signaling pathway和rap1 signaling pathway与心肌缺血密切相关。由于HIF-1信号通路是有机体的低氧应激通路,在低氧下能迅...
Vol.:(0123456789)13JCompPhysiolBDOI10.1007/s00360-017-1083-8ORIGINALPAPERIdenti cationo HIF-1signalingpathwayin PelteobagrusvachelliusingRNA-Seq:e ectso acutehypoxiaand reoxygenationon oxygensensors,respiratorymetabolism,and hematologyindicesGuosong Zhang1,2 ·Cheng Zhao1,2 ·Qintao Wang1 ·Yichun Gu...
Whole transcriptomic sequencing shows significant upregulation of the hypoxia‐inducible factor 1‐alpha (HIF‐1α) signaling pathway and associated downstream targets. Furthermore, Western blot analysis confirms elevated HIF‐1α protein in Cell Line A cells at later generation. These results suggest ...
Transcription factors that are downstream to TGF-β1, IL-4, and IL-2 signaling are essential for Th9 cell differentiation, as the deficiency of either of TGF-β receptor (TGF-βR), IL-4R or IL-2R impairs Th9 cell differentiation1,2,3,17. Transcription factors such as PU.1 (Spi1)...
We reviewed the role of transcription factors HIF-1α and its signaling pathway in the occurrence of disease , and introduced to the relationship among HIF-1α and growth, development, inflammation and tumor , then carryed out the prospect, in order to better be used in biomedical. Key ...