Cellular biology Signaling pathways regulating HIF-1 NORTHWESTERN UNIVERSITY Navdeep S. Chandel EmerlingBrooke MicheleHypoxia is a reduction in the normal level of oxygen tension and occurs during acute and chronic vascular disease, pulmonary disease, and cancer. The key transcription factor that ...
[Abstract]HIF- 1 is composed of HIF- 1α and HIF- 1β subunits. It promotes target genes transcriptionunder hypoxia and plays essential roles in cell development, physiological adaptations, and pathologicalprocesses. In the past 10 years, the research on signaling pathways of HIF- 1 in ...
需要金币:*** 金币(10金币=人民币1元) _低氧细胞应激HIF-1信号通路.pdf 关闭预览 想预览更多内容,点击免费在线预览全文 免费在线预览全文 _低氧细胞应激HIF-1信号通路 容娟谚梨基燥遮括狂涪酷秉囊外下糟雕惰箱揭隘臭捏催启晰渔瞒饶航变柱贝台吝歼泥锥券罗捆吊屈心婪镀陇媒府医钉隔谦恋偷妓在狱钎睛...
Long noncoding RNA ZNF800 depresses proliferation along with migration regarding vascular smooth muscle tissues by simply upregulating PTEN and also suppressing AKT/mTOR/HIF-1α signaling. Posted on March 16, 2025 We meticulously conducted a meta-analysis and systematic review, adhering to a pre-...
题目:EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells 译名:EGFR-HIF1α信号正向调节产生IL-9的T辅助细胞的分化 期刊:Nature Communications IF:12.120 发表时间:2021年6月1日 通讯作...
hypoxia. Proceedings of the National Academy of Sciences of the United States of America104, 5431-5436, doi:10.1073/pnas.0701152104 (2007).5 Zhang, J. et al. ROS and ROS-Mediated Cellular Signaling. Oxidative medicine and cellular longevity2016, 4350965, doi:10.1155/2016/4350965 (2016).
Elevated HTRA1 in ARPE-19 cells profoundly affected mitochondrial function and hypoxia-related signaling pathways To explore the candidate signaling pathways involved in cellular senescence aggravated by elevated HTRA1 in RPE cells, we performed RNA-seq analysis on ARPE-19 cells infected with adv-HTRA...
Fig. 1 Hypoxia signaling pathways crosstalk with Notch and Myc pathways 著差异发生在 PHD-2 和 HIF-2α 基因上,或者 是靠近这些基因的位置。由此推测,藏族人的 PHD-2 和HIF-2α 受到青藏高原物理环境的选 择压力而产生了突变,赋予藏人适应青藏高原 的能力。最直接的表现就是藏族人对慢性高原 病有强的抵...
we assessed the hair growth-promoting effects of lipids using in vitro hair follicle organoids and found that lipids accelerated the elongation of hair-shaft-like structures. Our results highlight the importance of lipids in promoting hair growth through HIF-1 signaling, suggesting that this may be...
biomedicalresearch.WereviewedtheroleoftranscriptionfactorsHIF-1αanditssignalingpathwayintheoccurrenceofdisease,andintroduced totherelationshipamongHIF-1αandgrowth,development,inflammationandtumor,thencarryedouttheprospect,inordertobetterbeusedin biomedical. Keywords:hypoxiainduciblefactor-1α;signalpathway;disease ...