Ulinastatin attenuates renal fibrosis by regulating AMPK/HIF-1α signaling pathway-mediated glycolysisXuejiao Wei, Mengtuan Long, Zhongyu Fan, Yue Hou, Liming Yang & Yujun Du Scientific Reports volume 14, Article number: 28032 (2024) Cite this article ...
[关键词] 山奈酚ꎻ 脓毒症ꎻ 代谢重编程ꎻ 糖酵解ꎻ 肝脏doi:10 3969/ j issn 1002-1949 2023 04 006TheeffectofkaempferolonliverfunctioninjuryinsepticratsanditsrelationshipwithHIF-1α/HK2signalingpathway GaoJinꎬ YinJuanꎬ ShenWen-juanꎬ ShenWeiꎬ WangSi-yuanꎬ...
hif1及ahr信号通路在a549细胞中相互作用的研究-study on interaction between hi f1 and ahr signaling pathway in a549 cells 目录内蒙古医科大学学位论文原创性声明中文摘要···(1)英文摘要···
Learn here about the HIF-1 signaling pathway and its impact on oxygen homeostasis and cellular adaptation. Click here.
Our results highlight the importance of lipids in promoting hair growth through HIF-1 signaling, suggesting that this may be a promising target for the treatment of hair loss.Scientific Reports
the Research Progress on the Regulatory Role of HIF - la Signaling Pathway孔健达 , 穆玉晶 , 朱磊 Kong Jianda , Mu Yujing,Zhu Lei摘 要:近年来 , 有大量研究表明 HIF-la 可作为癌症治疗的一个靶点 , 而运动抗癌亦被广泛认可 , 其作用 机制与 HIF-la 相关信号通路密不可分 , 但其具体机制研究尚...
mTOR信号通路可能通过影响F游 roTOR可整合体 内多条信号通路,~NPI3K/Akt/mTOR 细胞 f的表达而调控蛋门质合成,细胞凋亡等生 通路、Akt/TSC1.TSC2/Rheb/mTOR通路及LKB1一 物过程 。研究表明mT0R与细胞因子如缺m诱导网子 AMPK—TSC—mTOR通路等,在机体异常增殖、能量 (hypoxia.induciblefactor,HIF一1a),m管...
Interestingly, WISP3 effectively activated Wnt signaling pathway, and knockdown of WISP3 effectively blocked the influence of fibronectin on the migration, invasion and vascular structure formation potential of NSCLC cells. Our data also manifested that fibronectin elevated the transcription of WISP3 gene...
Subsequently, Nrf2-dependent Trx1 induction turned out to enhance HIF-1α signaling in intermittent hypoxia. Introduction HIF-11 and Nrf2 represent oxygen- and redox state-dependent transcription factors. HIF-1 is important in adapting cells to conditions of limited oxygen supply by affecting oxygen ...
In summary, Dexmedetomidine can partially attenuate lung injury in obstructive jaundice rats by PI3K/Akt/HIF-1α signaling pathway. Meanwhile, obstructive jaundice can increase the expression of IL-6 and TNF-α in the serum of rats. Dexmedetomidine can significantly reduce the expression of inflammato...