HIF-1α pathway: role, regulation and intervention for cancer therapy[J]. Georgina N.Masoud,Wei Li.Acta Pharmaceutica Sinica B. 2015(05)Masoud GN, Li W. HIF-1alpha pathway: role, regulation and intervention for cancer therapy. Acta Pharm Sin B. (2015) 5:378-89. doi: 10.1016/j.apsb...
关键词 : 缺氧诱导因子 -1α ;信号通路 ;疾病 DOI :10.13560/j.cnki.biotech.bull.1985.2016.08.002 Research Progress on the Role of Transcription Factor HIF-1α and Its Signal Pathway in the Pathogenesis YANG Meng-si ZHOU Na WANG Zhi-gang HAO Hui-fang (College of Life Sciences,Inner Mongolia ...
HIF1Alpha_Pathway之经典信号通路.ppt,HSP70 HIF1a Pathway Elongin-B Elongin-C Elongin-B p53 MKK3 MKK6 ERK2 FIH1 Ref1 PHD2 PHD1 TCP1a HSP90 MDM2 Ub HIF1a HIF1a HIF1a HIF1a HIF1a HIF1a Per1 JAB1 Ub Ub Ub Ub Ub VHL VHL ARNT HNF4a2 SRC1 HIF1a Degradation HIF1a
低氧诱导因子(…I:-1Q)在继发性脊髓损伤中的时序 性表达及其意义 一、前言 脊髓损伤(SCI)是一种严重影响人类健康和生活质量的致残性损伤【11。急性 脊髓损伤后开始时常为不完全性,最后结果常为两种损害机制引起:原发性脊髓 损伤和继发性脊髓损伤。脊髓组织遭受机械外力损伤后瞬间引起的组织损害称为 ...
具体内容发表在 Stem Cell Research & Therapy 期刊题为“A reduced level of the long non-coding RNA SNHG8 activates the NF-kappaB pathway by releasing functional HIF-1alpha in a hypoxic inflammatory microenvironment”。 首先,实验通过施加正畸力3天建立 OTM 模型。免疫组化染色显示,HIF-1α 在磨牙近...
具体内容发表在Stem Cell Research & Therapy期刊题为“A reduced level of the long non-coding RNA SNHG8 activates the NF-kappaB pathway by releasing functional HIF-1alpha in a hypoxic inflammatory microenvironment”。 首...
Conclusion GSG therapy can blockade of AM progression by inhibiting PI3K/Akt/HIF-1α pathway in in vivo experiments, with the selected GSG dose showing no significant adverse reactions in animals, indicating it is a potential treatment option for AM. Key words: Guizhi Fuling Capsules-Sanjie Zhen...
a group of novel hif-1 alpha inhibitors, glyceollins, blocks hif-1 alpha synthesis and decreases its stability via inhibition of the pi3k/akt/mtor pathway and hsp90 bindingj. journal of cellular physiology, 20 7、15,230(4):853-862. 4 zeng d, wang j, kong p, et al. ginsenoside rg3...
首页/研究领域/HIF1-alpha Pathway/ Human HIF-1 alpha ELISA Human HIF-1 alpha ELISA RayBio®Human HIF-1 alpha ELISA Kit for cell culture supernatants, plasma, and serum samples. CODE:ELH-HIF1a-1 Antigen Information Accession Number:
具体内容发表在 Stem Cell Research & Therapy 期刊题为“A reduced level of the long non-coding RNA SNHG8 activates the NF-kappaB pathway by releasing functional HIF-1alpha in a hypoxic inflammatory microenvironment”。 首先,实验通过施加正畸力3天建立 OTM 模型。免疫组化染色显示,HIF-1α 在磨牙近...