HIF-1α pathway: role, regulation and intervention for cancer therapy[J]. Georgina N.Masoud,Wei Li.Acta Pharmaceutica Sinica B. 2015(05)Masoud GN, Li W. HIF-1alpha pathway: role, regulation and intervention for cancer therapy. Acta Pharm Sin B. (2015) 5:378-89. doi: 10.1016/j.apsb...
(HIF)pathway,hasbeenshowntobeimportantinskeletaldevelopmentandregeneration.Therefore,weexaminedtheeffectsofpharmacologicagentsthatactivatetheHIFpathwayinvitroinbonemarrowstromalcellsandinvivoinastabilizedfracturemodel.TheagentswerefoundtoactivatehypoxicresponseelementsandinduceexpressionofVEGFinvitro.Correspondingly,PHD...
443种HIF-1信号通路化合物的集合,可用于细胞氧感知相关研究。 规格 预溶于DMSO或水 100uL/well 询价获取超大折扣 全国免费电话:400-668-6834 | Email:info@selleck.cn 您可以选择: 特定分子选择 规格 分子所置板上位置 粉末或DMSO溶液 客户使用该化合物库发表的文献286篇: ...
关键词:缺氧诱导因子-1α;信号通路;疾病DOI:10.13560/jki.biotech.bull.1985.2016.08.002ResearchProgressontheRoleofTranscriptionFactorHIF-1αandItsSignalPathwayinthePathogenesisYANGMeng-siZHOUNaWANGZhi-gangHAOHui-fang(CollegeofLifeSciences,InnerMongoliaUniversity,Hohhot010021)Abstract:Hypoxiainduciblefactor-1α(HIF...
[关键词]低氧诱导因子 1;低氧;反应元件;转录因子Q 494[文献标志码][中图分类号]A[文章编号]1008- 9292( 2011)05- 0559- 08HIF- 1 signal pathway in cellular response to hypoxiaWANG Ping-ping,KONG Fan-ping,CHEN Xue-qun,DU Ji-zeng ( Department of Basic Medical Sciences,Zhejiang University School...
We reviewed the role of transcription factors HIF-1α and its signaling pathway in the occurrence of disease , and introduced to the relationship among HIF-1α and growth, development, inflammation and tumor , then carryed out the prospect, in order to better be used in biomedical. Key ...
A Group of Novel HIF-1 alpha Inhibitors, Glyceollins, BlocksHIF-1 alpha Synthesis and Decreases Its Stability via Inhibition of the PI3K/AKT/mTORPathway and Hsp90 BindingJ. 7、JOURNAL OF CELLULAR PHYSIOLOGY, 2015,230(4):853-862.4 Zeng D, Wang J, Kong P, et al. Ginsenoside Rg3 ...
阐明HIF-1和调节细胞内葡萄糖代谢的因子之间的机制和功能相互作用,这有望加深我们对癌细胞复杂特征的理解。 Rreference:HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance PMID :30634433 D...
通路(Pathway) Apoptosis CAS号(CAS NO.) 1227158-85-1 分子式(Formula) C26H26F3N7O2 分子量(Molecular Weight) 525.53 纯度(Purity) ≥98% 结构式(Structure) 运输和保存方法 粉末-25~-15℃保存,有效期3年;溶于溶剂,-85~-65℃保存,有效期2年 ...
Hypoxia Signaling Pathway Description Legend Hypoxia (low O2) is a pathophysiological condition resulting from the imbalance between cellular O2consumption and vascular perfusion. Hypoxia is a common feature of solid tumors associated with increased chemoradioresistance and poor patient prognosis. Metazoans ...