HEK293 is a cell line derived from human embryonic kidney cells grown in tissue culture. They are also known, more informally, as HEK cells. This particular line was initiated by the transformation and culturing of normal HEK cells with sheared adenovirus 5 DNA. The transformation resulted in t...
The need for new safe and efficacious therapies has led to an increased focus on biologics produced in mammalian cells. The human cell line HEK293 has bio-synthetic potential for human-like production attributes and is currently used for manufacturing of
Compared to the parental HEK293 cell line, lentiviral vector titers obtained using HEK293T cells are higher.1,2 The original HEK293 cell line was derived by transformation of a human primary embryonic kidney cell line using mechanically sheared DNA of adenovirus type 5 (Ad5).3 A 4-kb Ad5...
Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. 16: 869-871, 2002. PubMed: 11967234 92579: Standard Test Method for Determining the Virus-Eliminating Effectiveness of Liquid Hygienic Handwash and Handrub Agents Using the Finger...
61259: Shaw G, et al. Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. 16: 869-871, 2002. PubMed: 11967234 92579: Standard Test Method for Determining the Virus-Eliminating Effectiveness of Liquid Hygienic Handwash and Handrub...
HEK293 cells are the second most used cells in cell biology and the second most used mammalian cells in biopharmaceutical production [4,5]. They are used as platforms for the expression of recombinant proteins due to their high transfection efficiency, flexibility, and human origin [6,7,8,9]...
HEK293 cells are the second most used cells in cell biology and the second most used mammalian cells in biopharmaceutical production [4,5]. They are used as platforms for the expression of recombinant proteins due to their high transfection efficiency, flexibility, and human origin [6,7,8,9]...