Gene Summary Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is prot...
EGF Knockout HEK293T Cells (EGF基因敲除HEK293T细胞)是通过同时表达Cas9、目的基因sgRNA和puromycin抗性基因,并实现了目的基因CRISPR敲除的HEK293T细胞。本细胞中目的基因的敲除已经通过T7EI法的验证。本细胞株是多克隆细胞,可用于该目的基因的生物学功能研究,也可以用于该基因相应抗体的验证。
Population Status: Single Cell Clone Origin Product Line: GeneBLAzer® Reporter Gene: BLA (Beta-Lactamase) System Type: GeneBLAzer™ Target Entry: EDG3 Technique: FRET Detection Method: Fluorescent 储存 Contents: K1713 GeneBLAzer® EDG3-Gα15-NFAT-bla HEK293T cells(LiveBLAzer...
The need for new safe and efficacious therapies has led to an increased focus on biologics produced in mammalian cells. The human cell line HEK293 has bio-synthetic potential for human-like production attributes and is currently used for manufacturing of several therapeutic proteins and viral vectors...
As the availability of human cardiomyocytes from patients is extremely limited, genetic modification of human pluripotent stem cells (hPSCs; including human embryonic and induced pluripotent stem cells) and the utilization of cardiomyocytes (CMs) derived thereof (hESC- or hiPSC-CMs) serves as an ...
In immune cells, it controls fundamental processes such as proliferation, cell adhesion, and migration, while in cancer, SOCE and ORAI1 gene expression are dysregulated and lead to abnormal migration and/or cell proliferation. In the present study, we used the CRISPR/Cas9 technique to delete ...
In general, cells of mesenchymal origin appear to be stimulated by TGF-β1; whereas, hepatocytes, T and B lymphocytes, keratinocytes, and many epithelial cells are inhibited by the peptide. TGF-β1 interacts with Epidermal Growth Factor (EGF), Platelet Derived Growth Factor (PDGF), Fibroblast ...
Anti-Ki67 Antibody, clone 1O15, ZooMAb® Rabbit Monoclonal recombinant, expressed in HEK 293 cells; Synonyms: Antigen KI-67,Antigen Ki67,Antigen identified by monoclonal antibody Ki-67,Proliferation marker protein Ki-67 at Sigma-Aldrich
cells and demonstrate partial inhibition of currents by anti-APOL antibodies. We detect in primary human podocytes a similar cation current inducible by interferon-γ (IFNγ) and sensitive to inhibition by anti-APOL antibody as well as by a fragment ofT. bruceiSerum Resistance-Associated protein (...
(p < 0.01) of Hu2AAB1 and 87 ± 7% (p < 0.001) of Rat2ASB1 cells were adherent in the presence of serotonin, while 39 ± 10% and 11 ± 8% cells of the respective untreated cells, which served as controls, remained adherent (Fig.1A). Other than the ...