Marian F., YoungSuzanne C., Dieudonn??. (1999) Estrogen receptors in bone. Current Opinion in Orthopedics 10 , 361-366 /Marian F. Young, Suzanne C. Dieudonn??. (1999) Estrogen receptors in bone. Current Opinion in Orthopedics 10 , 361-366 /...
S. Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells. Mol. Endocrinol. 19, 1606–1617 (2005). Article CAS PubMed Google Scholar Kawano, H. et al. Suppressive function of androgen receptor in bone resorption. Proc. Natl Acad. Sci. ...
Bone metastasis is a prominent cause of morbidity and mortality in cancer. High rates of bone colonization in breast cancer, especially in the subtype expressing estrogen receptors (ERs), suggest tissue-specific proclivities for metastatic tumor formation. The mechanisms behind this subtype-specific or...
展开 关键词: Bone and Bones Bone Marrow Humans Breast Neoplasms Receptors, Estrogen RNA, Messenger In Situ Hybridization Polymerase Chain Reaction Transcription, Genetic Reference Values DOI: 10.1016/S8756-3282(96)00346-8 被引量: 278 年份: 1997 收藏...
In order to investigate the possible role of estrogen in the development of cartilage and bone we studied by immunofluorescence immunohistochemistry and autoradiography 26 human embryos and fetuses 7-22 weeks in gestational age associated with pregnancy interrupted for non-medical reasons. In order to ...
Estrogen is critical for skeletal homeostasis and regulates bone remodeling, in part, by modulating the expression of receptor activator of NF-κB ligand (RANKL), an essential cytokine for bone resorption by osteoclasts. RANKL can be produced by a variet
The mechanisms by which estrogen exerts its effects on bone are not completely understood. Nonetheless, estrogen does affect calcium balance, and evidence suggests a direct mechanism via estrogen receptors on bone. The role of progestins in preventing bone loss is less well understood than that of...
It has long been appreciated that the estrogen receptor (ER) plays an important role in the biology of breast cancer. It is an accepted factor predicting f
Estrogen and SERMs primarily act by regulating gene transcription via estrogen receptors (ERα, ERβ) (Couse and Korach, 1999, Shang and Brown, 2002). ERs belong to the nuclear receptor gene superfamily and act as ligand-inducible transcriptional factors (Mangelsdorf et al., 1995). ER dimers...
Mentioned in: Anabolic Steroid Use, Bone Disorder Drugs, Cholesterol, High, Endometrial Cancer, Endometriosis, Fibroadenoma, Gynecomastia, Hormone Replacement Therapy, Menopause, Osteoporosis, Overactive Bladder, Premenstrual Syndrome, Saw Palmetto Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group...