Estrogen receptors alpha and beta in bone. Bone 2016, 87, 130-135. [CrossRef]Khalid AB & Krum SA 2016 Estrogen receptors alpha and beta in bone. Bone 87 130-135. (doi:10.1016/j.bone.2016.03.016)Khalid AB, Krum SA. Estrogen receptors alpha and beta in bone. Bone. 2016;87:130...
4.4.1Estrogens, estrogen receptor alpha and, estrogen receptor beta Estrogen receptoralpha is one of the canonical classifiers of breast cancermalignancies. It is central to theclinical classificationof breast cancers.Estrogen receptor betafunction is not as well documented in breast cancers (McNamara et...
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Bone metastasis is a prominent cause of morbidity and mortality in cancer. High rates of bone colonization in breast cancer, especially in the subtype expressing estrogen receptors (ERs), suggest tissue-specific proclivities for metastatic tumor formation. The mechanisms behind this subtype-specific or...
et al. Estrogen receptor-alpha signaling in osteoblast progenitors stimulates cortical bone accrual. J. Clin. Invest. 123, 394–404 (2013). Article CAS PubMed Google Scholar Borjesson, A. E. et al. The role of estrogen receptor-α and its activation function-1 for growth plate closure in...
Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa)). Estrogen receptors are widely expressed in different tissue types and are essential for sexual develo...
Production of proinflammatory cytokines and chemokines during neuroinflammation: novel roles for estrogen receptors alpha and beta Endocrinology, 151 (2010), pp. 4916-4925 CrossrefView in ScopusGoogle Scholar Byers and Holtzman, 2011 Byers D.E., Holtzman M.J. Alternatively activated macrophages and ai...
Estrogen receptor alpha (ERα) signaling has beneficial skeletal effects in males. ERα signaling also affects other tissues, and to find bone-specific treatments, more knowledge regarding tissue-specific ERα signaling is needed. ERα is subjected to posttranslational modifications, including phosphoryl...
Responsible for female sexual characteristics, estrogen stimulates and triggers a response from at least 300 tissues, and may help some types of breast cancer to grow. After menopause, the production of the hormone gradually stops. Mentioned in: Anabolic Steroid Use, Bone Disorder Drugs, ...
Evidence for functional estrogen receptors alpha and beta in human adipose cells: regional specificities and regulation by estrogens. Am J Physiol Cell Physiol. 286, C655–661 (2004). Article PubMed Google Scholar Barros, R. P., Gabbi, C., Morani, A., Warner, M. & Gustafsson, J. A....