The emergence of nanotechnology applied to medicine has revolutionized the treatment of human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs have evolved in terms of their specificity and efficiency, especially because of the possibility of using more effective ...
The emergence of nanotechnology applied to medicine has revolutionized the treatment of human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs have evolved in...doi:10.1186/s13148-019-0675-4Annalisa Roberti...
Treatment of SETD2-deficient or wild-type kidney cancer cells with an AKT-specific inhibitor resulted in similar effects. Therefore, these studies demonstrate that loss of SETD2 is synthetically lethal with PI3Kβ inhibition. They also show that AKT is a key part of the interaction between SET...
Epigenetics and cancer treatment EpigeneticsCancer therapyEpi-drugHistone deacetylase inhibitorDNA methyltransferase inhibitorIn addition to the genetic alterations, observed in cancer cells, are ... LS Kristensen,HM Nielsen,LL Hansen - 《European Journal of Pharmacology》 被引量: 483发表: 2009年 Epigenet...
For many people undergoing cancer treatment, chemotherapy is their best hope for recovery or remission. However, chemo may not always be effective enough, and combining it with other drugs or therapies can sometimes lead to serious side effects. Therefore, finding a safer alternative approach is ne...
Anti-tumor drug remains the primary treatment for most disseminated cancers. However,the response to anti-tumor drug is often transient,and development of resistance is one of the most significant obstacles to effective cancer therapy. The molecular mechanisms underlying cancer resistance are only partia...
Epigenetics in cancer N . Engl J Med. 2008; 358 :1148–1159.Jens U.Marquardt, Peter R.Galle, AndreasTeufel. (2012) Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): An emerging field for advanced ... M Esteller 被引量: 773发表: 2008年 Epigenetics and cancer treatment In...
Angela Ting, Ph.D., was intrigued by the field of epigenetics as soon as she was introduced to it in college. Now, she runs a research lab that explores how epigenetics plays a role in the development of cancer. She wants to use that knowledge to better
An improvement in pancreatic cancer treatment represents an urgent medical goal.Late diagnosis and high intrinsic resistance to conventional chemotherapy has led to a dismal overall prognosis that has remained unchanged during the past decades.Increasing knowledge about the molecular pathogenesis of the ...
epigenetics and animal models: applications in cancer control and treatment chapter outline Infectious agents are one of the factors which contribute to cancer development. Few examples include human papilloma virus in cervical cancer, hepatitis v... M Verma,N Agarwal,M Verma 被引量: 3发表: 2014...