Twin studies have estimated the heritability at about 37% and these estimation can rise up to 70% if severity, relapse rate and age of onset are considered. Despite the relative importance of genetic risk factors in the pathogenesis of this disease, molecular genetic studies, including large ...
Epigenetic changes in prostate cancer: implication for diagnosis and treatment. literature on epigenetic changes in prostate cancer and discuss the clinical potential of cancer epigenetics for the diagnosis and treatment of this disease.do... LC Li,PR Carroll,R Dahiya - 《Journal of the National Ca...
Epilepsy is a common episodic neurological disorder or condition characterized by recurrent epileptic seizures, and genetics seems to play a key role in it... Tian,Chen,Mohan,... - 《Neuropsychiatric Disease & Treatment》 被引量: 12发表: 2017年 Epigenetic Economic Dynamics: The evolution of big...
Epigenetics and pancreatic cancer: pathophysiology and novel treatment aspects. World J. Gastroenterol. 20, 7830-7848. doi:http://dx.doi.org/10.3748/wjg.v20. i24.7830.Neureiter, D.; Jager, T.; Ocker, M.; Kiesslich, T. Epigenetics and pancreatic cancer: Pathophysiology and novel treatment...
The part that epigenetic modifications play in the development of childhood health and disease is being established by ongoing research and discoveries in this field. Right after the establishment of the genetic blueprint at the time of fertilization and
The microbiota plays a role in the health and disease status of the host. Their number, species dominance, and viability are dynamic. Their long-term disturbance is usually accompanied by serious diseases such as metabolic disorders, cardiovascular diseases, or even cancer. While epigenetics is a ...
The morbidity and mortality from ischemic heart disease (IHD) remain significant worldwide. The treatment for acute myocardial infarction has improved over... JPG Sluijter,G Condorelli,SM Davidson,... - 《Pharmacology & Therapeutics》 被引量: 64发表: 2014年 Epigenetic dysregulation in schizophrenia:...
Environmental epigenetic regulation in asthma and allergic disease is an exciting area that has gained a great deal of scientific momentum in recent years. Environmental exposures, including prenatal maternal smoking, have been associated with asthma-related outcomes that may be explained by epigenetic re...
COPD (or chronic obstructive pulmonary disease) is a term used to describe progressive lung diseases including chronic bronchitis and emphysema. Long-term exposures to irritants that damage the lungs contribute to COPD, andsmokingis considered the leading cause. According to theWorld Health Organization...
Presents side-by-side coverage of the basis of epigenetic diseases and treatment pathways Each chapter updated to include summaries, definitions, and vibrant imagery and figures to reinforce understanding Features step-by-step methods and disease research case studies to put book concepts into practice...