8. Iwasa H, Yu S, Xue J, Driscoll M. Novel EGF pathway regulatorsmodulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation. Aging Cell. 2010 Aug; 9(4):490-505. ◆上海晶诺生物科技有限公司◆ 严格的质控体系 成熟的蛋白质表达和纯化平台 并有细胞因子生物...
15. Ueno H, Sasaki K, Miyagawa K, Honda H, Mitani K, Yazaki Y, Hirai H. 1997. Antisense Repression of Proto-oncogene c-Cbl Enhances Activation of the JAK-STAT Pathway but Not the Ras Pathway in Epidermal Growth Factor Receptor Signaling. Journal of Biological Chemistry. 272(13):8739-874...
E3B1 (EPS8 Binding Protein)/ABI1 (Abl-Interactor-1) is a protein involved in the EGFR signalling pathway. E3B1/ABI1 interacts with EPS8 (Epidermal Growth Factor Receptor Pathway Substrate-8), a protein which is phosphorylated in fibroblasts in response to EGF. Remarkably, E3B1/ABI1 is a...
D. (2010). Primary and secondary therapeutic strategies for EGF receptor pathway inhibition in non-small-cell lung cancer . Expert Rev Anticancer Ther 10 , 1589–159910.1586/era.10.104 [ Cross Ref ]Batus M,Fidler MJ,Bonomi PD.Primary and secondary therapeutic strategies for EGF receptor pathway ...
woundhealing.MutationoftheEGFreceptorhasbeenassociatedwithcancerinhumans.TheproliferativeeffectsofEGFaresignaledthroughseveralpathways.BindingofEGFresultsinEGFreceptordimerization,autophosphorylationofthereceptor,andtyrosinephosphorylationofotherproteins.TheEGFreceptoractivatesrasandtheMAPkinasepathway,ultimatelycausing...
EGF Receptor(1F4) Mouse mAb specifically detects EGF receptors expressed in A431 and MDA-MD-468 cells, but does not cross-react with ErbB2, 3, and 4 proteins expressed in MDA-MD-453 and MCF-7 cells. Show more Western blot analysis of extracts from the indicated cell lines. EGF ...
EGF receptor-ERK pathway is the major signaling pathway that mediates upregulation of aldose reductase expression under oxidative stress. Free Radical Biol. Med. 2001, 31, 205-216.Nishinaka T,Yabe-Nishimura C.EGF receptor-ERK pathway is the major signaling pathway that mediates upregulation of ...
15. Ueno H, Sasaki K, Miyagawa K, Honda H, Mitani K, Yazaki Y, Hirai H. 1997. Antisense Repression of Proto-oncogene c-Cbl Enhances Activation of the JAK-STAT Pathway but Not the Ras Pathway in Epidermal Growth Factor Receptor Signaling. Journal of Biological Chemistry. 272(13):8739-874...
crucial role in growth factor and hormone receptor down-regulation, this signaling pathway has also been proposed to regulate endosomal membrane transport and multivesicular endosome biogenesis. Here, we have followed the fate of the down-regulated EGF receptor (EGFR) and bulk transport (fluid......
美国田纳西州纳什维尔范德比尔特大学肾病中心的Raymond C. Harris团队,于2019年7月在知名学术期刊《J Am Soc Nephrol》上发表了题为“The Role of the EGF Receptor in Sex Differences in Kidney Injury”的文章[2],为我们揭示了肾脏损伤中存在性别差异这一有趣现象。研究结果表明,EGF在性别间表达的差异可能是慢性...