EGF receptor (EGFR) signaling in human cancers elicits changes in protein-expression patterns that are crucial for potentiating tumor growth. Identifying those proteins with expression regulated by the EGFR and determining how they contribute to malignancy is fundamental for the ...
15. Ueno H, Sasaki K, Miyagawa K, Honda H, Mitani K, Yazaki Y, Hirai H. 1997. Antisense Repression of Proto-oncogene c-Cbl Enhances Activation of the JAK-STAT Pathway but Not the Ras Pathway in Epidermal Growth Factor Receptor Signaling. Journal of Biological Chemistry. 272(13):8739-874...
EGF / PDGF Signaling Pathway PCR ArrayRatGene ExpressionPARN-040Z Epidermal Growth Factor Receptor Signaling Pathway: BCAR1, CBL, EGF, EGFR, EPS8, GAB1, GRB2, HBEGF, NCK2, NUP62, RPS6KA5, SHC1. Platelet-Derived Growth Factor Receptor Signaling Pathway: BCAR1, PDGFA, PDGFB, PDGFRA, ...
15. Ueno H, Sasaki K, Miyagawa K, Honda H, Mitani K, Yazaki Y, Hirai H. 1997. Antisense Repression of Proto-oncogene c-Cbl Enhances Activation of the JAK-STAT Pathway but Not the Ras Pathway in Epidermal Growth Factor Receptor Signaling. Journal of Biological Chemistry. 272(13):8739-874...
EGF Receptor(1F4) Mouse mAb specifically detects EGF receptors expressed in A431 and MDA-MD-468 cells, but does not cross-react with ErbB2, 3, and 4 proteins expressed in MDA-MD-453 and MCF-7 cells. Show more Western blot analysis of extracts from the indicated cell lines. EGF ...
Convergence of integrins and EGF receptor signaling via PI3K/ Akt/FoxO pathway in early gene Egr-1 transcription. J Cell Physiol 2009; 218: 294–303Cabodi, S.; Morello, V.; Masi, A.; Cicchi, R.; Broggio, C.; Distefano, P.; Brunelli, E.; Silengo, L.; Pavone, F.; Arcangeli, ...
美国田纳西州纳什维尔范德比尔特大学肾病中心的Raymond C. Harris团队,于2019年7月在知名学术期刊《J Am Soc Nephrol》上发表了题为“The Role of the EGF Receptor in Sex Differences in Kidney Injury”的文章[2],为我们揭示了肾脏损伤中存在性别差异这一有趣现象。研究结果表明,EGF在性别间表达的差异可能是慢性...
美国田纳西州纳什维尔范德比尔特大学肾病中心的Raymond C. Harris团队,于2019年7月在知名学术期刊《J Am Soc Nephrol》上发表了题为“The Role of the EGF Receptor in Sex Differences in Kidney Injury”的文章[2],为我们揭示了肾脏损伤中存在性别差异这一有趣现象。研究结果表明,EGF在性别间表达的差异可能是慢性...
woundhealing.MutationoftheEGFreceptorhasbeenassociatedwithcancerinhumans.TheproliferativeeffectsofEGFaresignaledthroughseveralpathways.BindingofEGFresultsinEGFreceptordimerization,autophosphorylationofthereceptor,andtyrosinephosphorylationofotherproteins.TheEGFreceptoractivatesrasandtheMAPkinasepathway,ultimatelycausing...
The epidermal growth factor receptor (EGFR) is a protein embedded in the outer membrane of epithelial and mesenchymal cells, bone cells, blood and immune cells, heart cells, glia and stem neural cells. It belongs to the ErbB family, which includes three