PDTD: a web-accessible protein database for drug target identification. Gao Zhenting,Li Honglin,Zhang Hailei,Liu Xiaofeng,Kang Ling,Luo Xiaomin,Zhu Weiliang,Chen Kaixian,Wang Xicheng,Jiang Hualiang. BMC Bioinformatics . 2008Gao, Z. T.; Li, H. L.; Zhang, H. L.; Liu, X. F.; Kang, ...
We've built the most comprehensive, up-to-date, & accurate drug database on the market. Combining the advantages of AI and human expertise, we are able to source, validate, structure, and update our data every day so you don’t have to. ...
If one of the two interacting protein molecules is regarded as the “target” and the other as the “ligand”, in principle the “ligand” can be simplified into a relatively short peptide that keeps the essential elements needed for its binding to the “target”. Thus, truncating a proper...
With our Invitrogen and Gibco portfolios of protein kinases, ADME/Tox products, primary & stem cell products, target-based assays, and custom biology services we help you drive efficiency in assay development, high-throughput screening, and metabolic and safety assessment. NEW Ask us today about ...
The global set of relationships between protein targets of all drugs and all disease-gene products in the human protein–protein interaction or 'interactome' network remains uncharacterized. We built a bipartite graph composed of US Food and Drug Adminis
Z. TTD: Therapeutic Target Database. Nucleic Acids Res. 30, 412–415 (2002). Article CAS Google Scholar Wishart, D. S. et al. DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Res. 34, D668–D672 (2006). Article CAS Google Scholar ...
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Our drug discovery and development team providessupport,expertise,collaborationandcustomizationto meet your unique needs. With our Invitrogen and Gibco portfolios of protein kinases, ADME/Tox products,primary & stem cell products, target-based assays, andcustom biology serviceswe help you drive efficiency...
1 Drug target constraint by modality and indication. Mean (dots) and 95% confidence interval (line segments) for constraint in subsets of drug-targets sets (data sources and number of genes for each list are provided in Extended Data Table 1). Modality information was extracted from DrugBank ...
However, such information of most drug targets is dispersedly deposited in the literatures or other databases like Protein Data Bank (PDB). Therefore, it is in dire need of a database containing comprehensive information of the potential target proteins. Recently, some notable efforts have been ...