Effects of genetics variants of pregnant xenobiotic receptor and on pharmacogenetics anddrug metabolism; 人类孕烷受体遗传变异对遗传药理学和药物代谢的影响 3. Genetic polymorphism of cytochrome P450 anddrug metabolism; 细胞色素P450的基因多态性与药物代谢 ...
Cyprocide selectively kills nematodes via cytochrome P450 bioactivation Plant-parasitic nematodes have the potential to destroy crops globally, and limited options for managing nematode infestation are available. Here, the authors report the 1,3,4-oxadiazole thioether scaffold called Cyprocide that sele...
Drug Metabolism: Cytochrome P450 Reference Module in Biomedical Sciences 2021 Purchase options CorporateFor R&D professionals working in corporate organizations. Academic and personalFor academic or personal use only. Looking for a customized option? Contact sales for special pricing for your organizationCont...
Cytochrome P450(CYP) is a family of the body's more powerful detox enzymes that involves in the biotransformation of various endogenous and exogenous compounds including clinical drugs.Genetic and phenotypic polymorphism of CYP results in the individual differences of xenobiotic metabolisms.Nuclear recepto...
Cytochrome P450(CYP) is the principal oxidation enzymes responsible for the metabolism of manyanti-epileptic drugs. 细胞色素P450(CYP)氧化酶是许多抗癫 药物(AEDs)的代谢酶,许多研究证实CYP基因存在遗传多态性并存在种族差异,其多态性可影响抗癫 药物的血药浓度。
当当中国进口图书旗舰店在线销售正版《【预订】Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery ...》。最新《【预订】Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery ...》简介、书评、试读、价格、图
To investigate this apparent paradox, we evaluated both gemfibrozil and its major metabolite, an acyl-glucuronide (gemfibrozil 1-O-beta-glucuronide) as direct-acting and metabolism-dependent inhibitors of the major drug-metabolizing cytochrome P450 enzymes (CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6, ...
Myeloperoxidase Cytochrome P450 Drug metabolites Heme H2O2 Free radicals 1. Introduction Drug metabolism is the process by which a xenobiotic substrate is structurally altered in the body, usually via enzyme catalysis. In addition, a xenobiotic is a relatively small non-nutrient chemical that is exogen...
Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain (1993). Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain. Biochem. Pharma- ... Jean-Franç...