This boosted the development of DC-based cancer vaccines currently studied worldwide. So far, most clinical trials have vaccinated patients with ex vivo -generated monocyte-derived DCs (moDCs), matured in the presence of cytokines and loaded with tumour antigen via peptides, protein- or RNA-...
Generation of dendritic cell-based vaccines for cancer therapy. Dendritic cells play a major role in the generation of immunity against tumour cells. They can be grown under various culture conditions, which influence t... G Reinhard,A Marten,SM Kiske,... - 《British Journal of Cancer》 被引...
Cancer immunotherapy is a growing field that focuses on manipulating the immune system to better target cancer. Dendritic cells (DCs) have been identified as a potential component of cancer vaccines. DCs present tumor-specific antigens to T cells in order to generate tumor-specific immunity. ...
Progress of dendritic cell-based cancer vaccines for patients with hematological malignancies Introduction: Dendritic cells (DCs) are the most professional antigen-presenting cells eliciting cellular and humoral immune responses against cancer cells... MSA Ni - 《Expert Opinion on Biological Therapy》 被...
2002. Dendritic cell-based vaccines and therapies for cancer. Expert Opin. Biol. Ther. 2: 919-928.Tatsumi T, Storkus WJ. Dendritic cell-based vaccines and therapies for cancer. Expert Opin Biol Ther 2002;2(8):919–28.Tatsumi T, Storkus WJ. Dendritic cell-based vaccines and therapies ...
Tumor endothelial marker 8 expression levels in dendritic cell-based cancer vaccines are related to clinical outcome[J] . Franco Maria Venanzi,Massimiliano Petrini,Laura Fiammenghi,Elisabetta Bolli,Anna Maria Granato,Laura Ridolfi,Federica Gabrielli,Alessandra Barucca,Antonio Concetti,Ruggero Ridolfi,Angela...
At the interface between the innate and adaptive immune system, dendritic cells (DCs) play key roles in tumour immunity and hold a hitherto unrealized potential for cancer immunotherapy. Here we review the role of distinct DC subsets in the tumour microe
Many strategies have been developed to target DCs in cancer, such as the administration of antigens with immunomodulators that mobilize and activate endogenous DCs, as well as the generation of DC-based vaccines. A better understanding of the diversity and functions of DC subsets and of how ...
Dendritic cell-based therapeutic cancer vaccines: what we have and what we need. Therapeutic cancer vaccines rely on the immune system to eliminate tumor cells. In contrast to chemotherapy or passive (adoptive) immunotherapies with anti... P Kalinski,J Urban,R Narang,... - 《Future Oncology》...
Immunotherapy of cancer with dendritic-cell-based vaccines. Cancer Immunol Immunother 46, 82–87 (1998). https://doi.org/10.1007/s002620050465 Download citation Issue DateApril 1998 DOIhttps://doi.org/10.1007/s002620050465 Share this article Anyone you share the following link with will be able ...