Each topic is connected with ICT in some manner but is also a fundamental aspect of cell-mediated immunity directed toward intracellular pathogens.doi:10.1146/annurev-med-062518-045435TL.MurphyKM.MurphyCellular & Molecular ImmunologyDendritic cells in cancer immunology - Fong, Engleman - 2000 () ...
Dendritic Cells in Cancer The preferential ability of conventional dendritic cells (cDCs) to activate T cells is the foundation of the ‘cancer immunity cycle’ outlined by Chen and Mellman [1]. Tumor-associated cDCs are thought to endocytose dead neoplastic cells or cellular debris and transport...
Dendritic cells and monocyte-derived cells: two complementary and integrated functional systems. Semin. Cell Dev. Biol. 41, 9–22 (2015). Article CAS PubMed Google Scholar Böttcher, J. P. & Reis e Sousa, C. The role of type 1 conventional dendritic cells in cancer immunity. Trends ...
For a cancer vaccine to be effective, numerous requirements must be satisfied in order to induce the desired immune response illustrated in Fig. 1. First, antigens need to be delivered to antigen presenting cells (APCs), including dendritic cells (DCs) but also macrophages, neutrophils, and lym...
" Dendritic Cells and Immunotherapy for Cancer, " Int. J. Hematol. 77(5):439-443.Chang DH, Dhodapkar MV. (2003). Dendritic cells and immunotherapy for cancer. Int J Hematol, 77 (5), 439-43.Chang DH, Dhodapkar MV. Dendritic cells and immu- notherapy for cancer. Int J Hematol ...
The development of cDC1 cells require BATF3 [10]. Selective depletion studies have demonstrated the importance of cDC1 in viral immunity and defense from intracellular infection [7]. cDC1 derivation is an aim of DC-based cancer therapies because of their potential in ...
Dendritic cells (DCs) are a heterogeneous population of antigen-presenting cells that act to bridge innate and adaptive immunity. DCs are critical in mounting effective immune responses to tissue damage, pathogens and cancer. Immature DCs continuously sample tissues and engulf antigens via endocytic pa...
Type I interferons (IFNs) facilitate cancer immunosurveillance, antitumor immunity and antitumor efficacy of conventional cell death-inducing therapies (ch... Yamaguchi,Yoshiyuki 被引量: 0发表: 2016年 [Dendritic cells and immunotherapy of liver cancer]. Type I interferons (IFNs) facilitate cancer imm...
F. I. Van Tendeloo, and Z. N. Berneman. 2003. Cancer immunotherapy using RNA-loaded dendritic cells. Clin. Exp. Immunol. 134: 378-384.P. Ponsaerts, V.F.I. Van Tendeloo, Z.N. Berneman, Cancer immunotherapy using RNA-loaded dendritic cells, Clin. Exp. Immunol. 134 (2003) 378-384...
DCs control both tolerance and immunity. Therefore, DCs are key targets for both preventive and therapeutic vaccination. Herein, we will discuss the physiology of DCs as it applies to immunotherapy of cancer.关键词: Dendritic Cells Animals Humans Neoplasms Cancer Vaccines Antigens, Neoplasm ...