Dendritic cells in cancer immunology - Fong, Engleman - 2000 () Citation Context ...perimental findings: immunotherapy, and tumour vaccines in particular, may result in a complete or partial remission of the tumour, the stabilization of its growth, or it may fail (Chen and Wu, 1998; =-=...
Dendritic cells in cancer immunology Article Open access 03 September 2021 Dendritic cell maturation in cancer Article 07 February 2025 References Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646–674 (2011). Article CAS PubMed Google Scholar Mittal, ...
Dendritic cells (DCs) are antigen-presenting cells (APCs) that play a crucial role in bridging innate and adaptive immune responses [1]. DCs patrol the local environment through the extensive expression of membrane and cytosolic receptors that recognize different types of danger signals, including pa...
Dendritic cells in cancer immunology 来自 NCBI 喜欢 0 阅读量: 26 作者:T Murphy,K Murphy 摘要: The clinical success of immune checkpoint therapy (ICT) has produced explosive growth in tumor immunology research because ICT was discovered through basic studies of immune regulation. Much of the ...
Cancer immunotherapy, alone or in combination with conventional therapies, has revolutionized the landscape of antineoplastic treatments, with dendritic cells (DC) emerging as key orchestrators of anti-tumor immune responses. Among the distinct DC subsets, conventional type 1 dendritic cells (cDC1) have...
Thus, several strategies have explored antigens delivery directly to DCs in vivo. Show abstract Decisions about dendritic cells: Past, present, and future 2012, Annual Review of Immunology Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents nec...
The use of dendritic cells in cancer immunotherapy. A novel approach to vaccination against cancer is to exploit dendritic cells (DCs) as 'nature's adjuvants' and actively immunize cancer patients with a sam... G Schuler,B Schuler-Thurner,RM Steinman - 《Current Opinion in Immunology》 被引...
Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such are necessary for T-cell-mediated cancer immunity. In particular, antitumoral responses depend on a specialized subset of conventional DCs that transport tumor antigens to draining lymph nodes and cross-present...
Dendritic cells (DCs) are a heterogeneous population of antigen-presenting cells that act to bridge innate and adaptive immunity. DCs are critical in mounting effective immune responses to tissue damage, pathogens and cancer. Immature DCs continuously sample tissues and engulf antigens via endocytic pa...
Eggermont and Carl G. Figdor provide an overview of immunotherapeutics for cancer treatment that harness dendritic cells, their challenges in clinical use, and approaches employed to enhance their recruitment and activation to promote effective anti-tumour immunity.关键词:...