Seminars in ImmunopathologyHansen M, Andersen MH. The role of dendritic cells in cancer. Semin Immunopathol. 2017;39.3:307-316.Hansen M and Andersen MH. The role of den- dritic cells in cancer. Semin Immunopathol 2017; 39: 307-316.
Dendritic cells (DCs) are potent antigen-presenting cells (APCs) that play an important role in inducing primary antigen-specific immune responses. Some vi... HAD Yue,XW A,WF E,... - 《Veterinary Microbiology》 被引量: 0发表: 2019年 Dendritic cell-based cancer immunotherapy: the stagnant ...
Myeloid cells can favour or hinder each step of the metastatic cascade. Myeloid cells have a central, yet still largely unexplored, role in virtually all therapeutic modalities, including surgery, chemotherapy, radiotherapy, immunotherapy and targeted therapy. Modulating myeloid cell functions in therapy...
This process occurs not only within the local tumour microenvironment but also in various distant body compartments. Myeloid cells can favour or hinder each step of the metastatic cascade. Myeloid cells have a central, yet still largely unexplored, role in virtually all therapeutic modalities, ...
Role of inflammatory cells during cancer progression How do cancer cells avoid destruction by the immune system? It is currently accepted that anaberrant innate and adaptive immune responsecontributestotumorigenesisbyselecting aggressive clones, inducing immunosuppression, and stimulating cancer cell proliferatio...
Revisiting the role of CD4+ T cells in cancer immunotherapy—new insights into old paradigms Article Open access 27 May 2020 References Hayday, A. C. et al. Structure, organization, and somatic rearrangement of T cell gamma genes. Cell 40, 259–269 (1985). Article CAS PubMed Google Sc...
Crucial role of dendritic cells in the generation of anti-tumor T-cell responses and immunogenic tumor microenvironment to suppress tumor development Dendritic cells (DCs) are known as unique professional antigen (Ag)-presenting cells (APCs) to prime nave T cells for the initiation of adaptive immu...
Lysosomes are an important component of the inner membrane system and participate in numerous cell biological processes, such as macromolecular degradation, antigen presentation, intracellular pathogen destruction, plasma membrane repair, exosome release
Moreover, lysosomes play an important role in autophagy. In mammalian cells, autophagy stimulation signals such as starvation can activate ULK complex (ULK1/2, FIP200, Atg13), which marks the initiation of formation of the phagophore. The recruitment of PI3K complex (VPS34, VPS15, Beclin1 an...
Cancer is a complex disease, and despite incredible progress over the last decade, it remains the leading cause of death worldwide. Liver cancers, including hepatocellular carcinoma (HCC), and liver metastases are distinct from other cancers in that they