tumour-specific vaccineimmunologic adjuvants.Dendritic cells (DC) are professional antigen-presenting cells whose primary function is the initiation of immune response. Based on the finding that the immune system usually fails to identify and kill cancer cells, DC have been recently used as vaccines ...
A DNA nanodevice-based vaccine for cancer immunotherapy Shaoli Liu Qiao Jiang Baoquan Ding Nature Materials(2021) Advertisement Nature Reviews Immunology(Nat Rev Immunol) ISSN1474-1741(online) ISSN1474-1733(print) Sign up for theNature Briefingnewsletter — what matters in science, free to your inbo...
Although concerns for pDC-mediated immunosuppression may exist39,40,41, the aforementioned pre-clinical and clinical results suggest that pDCs may hold promise as effective anti-cancer vaccine constituents. Multiplexed DC vaccines Undoubtedly, all DC subsets likely contribute to generating anti-tumour ...
Dendritic cell-based tumor vaccine for cervical cancer II: results of a clinical 12 pilot study in 15 individual patients. J Cancer Res Clin Oncol. 2003; 129 :521–530. doi: 10.1007/s00432-003-0463-5. [ Cross Ref ]Ferrara A, Nonn M, Sehr P et al (2003) Dendritic cell-based tumor...
Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancerThe present disclosure provides compositions comprising mature dendritic cells loaded with autologous tumor cell lysates for the treatment of liver cancers, such as hepatocellular carcinoma. Hepatocellular carcinoma (HCC) is ...
Development of a Dendritic Cell (DC) Vaccine for Advanced Colorectal Cancerdoi:10.1007/978-1-4615-0547-1_23Colorectal cancer is one of the most common malignancies encountered in the Western World and in-spite of the development of treatment strategies involving adjuvant chemotherapy, hepatic ...
Dendritic cell (DC) vaccine: DC are specialized antigens presenting cells to the T cell receptor to generate robust immune response against the antigens and cancer cells. From: Design of Nanostructures for Theranostics Applications, 2018 About this pageSet alert Also in subject areas: Immunolog...
The dendritic cells and the cancer stem cells irradiated with the radiation are co-cultured for activating the dendritic cells into cancer-stem-cell-antigen-presenting dendritic cells to obtain the dendritic cell tumor vaccine. The dendritic cell tumor vaccine is a mixture of the cancer-stem-cell-...
Another peptide sequence of hTERT p865 (RLVDDFLLV) has also been tested for vaccination and has shown effective antitumor response [4,34,35]. GRNVAC1 (Geron Corporation, Menlo Park, CA) is a dendritic-cell-based vaccine for cancer. In this approach mature autologous DC, isolated from ...
A dendritic cell vaccine for both vaccination and neoantigen-reactive T cell preparation for cancer immunotherapy in mice Adoptive cell transfer (ACT) using neoantigen-specific T cells is an effective immunotherapeutic strategy. However, the difficult isolation of neoantigen-specific T cells limits the ...