Extracellular vesicles: a new prospective in crosstalk between microenvironment and stem cells in hematological malignancies. Stem Cells Int. 2018;2018:9863194. Article PubMed Central PubMed Google Scholar Lapa C, Herrmann K, Schirbel A, Hanscheid H, Luckerath K, Schottelius M, et al. CXCR4...
a large number of immune cells, mainly including T cells and macrophages, will infiltrate [12]. Macrophages recruited in particular in prostatitis have been identified as key regulatory factors in prostatitis. In clinical practice, phospholipid vesicles are often used as an indicator...
have stated that CXCL12 participates in lymphocyte motility through binding and signaling through CXCR7 which is expressed on the primary T cell surface [30]. Similarly, in our work, we found high CXCR4 and CXCR7 levels in the placental tissues of puerperae with placenta previa, and silencing...
Acute myeloid leukemia cells functionally compromise hematopoietic stem/progenitor cells inhibiting normal hematopoiesis through the release of extracellular vesicles. Front Oncol. 2022;12:824562. Article PubMed PubMed Central CAS Google Scholar Kumar B, Garcia M, Weng L, Jung X, Murakami JL, Hu ...
It is thought that paracrine factors produced by the injured cerebral tissue attract progenitor/stem cells that in turn secrete a variety of trophic factors and extracellular vesicles that help to restore function of the ischemic region and enhance neuroplasticity (Beer et al., 2016). There are ...
[51,73].Although some studies have indicated that silencing CXCR4 in T-cell acute lymphoblastic leukemia can inhibit the expression of myc [74]. However, we first demonstrated the transcriptional regulation of Pfkfb3 by MYC in macrophages. But in the process of knocking down CXCR4, only Pfkfb...
21. Tang D, Xu X, Ying J, Xie T, Cao G. Transfer of metastatic traits via miR-200c in extracellular vesicles derived from colorectal cancer stem cells is inhibited by atractylenolide I. Clin Transl Med. 2020; 10:e139. https://doi.org/10.1002/ctm2.139 [PubMed] 22. Sabbah M, Emami...
Bowers, T.W. Schwartz, M. Marsh The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling Mol. Biol. Cell, 12 (2001), pp. 1737-1749 Google Scholar Fraile-Ramos et al., 2002 A. Fraile-Ramos, A. Pelchen-Matthews, T.N. ...
Despite the improved understanding of many mechanisms within this disease, global gene expression analysis has few focused studies on the fibroblast, the central effector cell of progressive fibrosis. We present a unique analysis of IPF pulmonary fibroblasts as they transition through cell culture and ...
Abstract Extensive research on the CXCL12-CXCR4 axis in acute myeloid leukemia (AML) has resulted in the incorporation of novel anti-leukemia drugs targeting this axis into therapeutic strategies. However, despite this progress, a comprehensive and up-to-date review addressing the role of the CXCL1...