A consequence is that the category of representations of any wild finite-dimensional algebra has width $\\\infty$ and hence, if the algebra is countable, there a superdecomposable pure-injective representation. It is conjectured that a stronger result is true: that a representation embedding...
B cells and T cells are important components of the adaptive immune system and mediate anticancer immunity. The T cell landscape in cancer is well characterized, but the contribution of B cells to anticancer immunosurveillance is less well explored. Here we show an integrative analysis of the B ...
Clonal structure, isotype distribution and convergent clonotypes in memory B cells To gain insight into the clonal composition of the human memory B cell pool, we used the high-throughput single-cell 10X Genomics platform to obtain >2.2 × 105paired VH/VL sequences from circulating memory...
Southern analysis and oligonucleotide hybridization experiments demonstrated that clonally related predominant and minor tumor cell populations were present in S at diagnosis, and that the minor population became the predominant population in the relapse specimens, N3 and N4. Although the Ig specificity ...
MH Terhune,KD Cooper - 《Archives of Dermatology》 被引量: 36发表: 1993年 Lymphomatoid papulosis with CD1a+ dendritic cell hyperplasia, mimicking Langerhans cell histiocytosis gene rearrangement studies confirmed a clonal T-cell population, which with the clinical history was consistent with the diagno...
All analyses were performed at a significance level of 5% with the statistical package SPSS 17.0 (Chicago, IL). Results Overview of the patient cohort The present series included 102 cases, 49 men and 53 women, retrospectively selected for the presence of a clonal B-cell population with immuno...
A population genetics perspective on the determinants of intra-tumor heterogeneity Cancer results from the acquisition of somatic alterations in a microevolutionary process that typically occurs over many years, much of which is occult. U... Z Hu,R Sun,C Curtis - Biochimica et Biophysica Acta (...
In conclusion, CD19<sup xmlns="http://pub2web.metastore.ingenta.com/ns/">+</sup> clonal cells include a population of cells persistent after high dose chemotherapy that may be responsible for relapse. 展开 关键词: B-cells CD19 Immunoglobulin gene rearrangement Multiple myeloma Single cell RT...
[92]. Heterogeneity within the exhausted CD8+T cell population of CLL was further revealed by Hanna et al., identifying the PD-1 intermediate expression (PD-1int) subset that was still functional and PD-1 high expression (PD-1hi) subset that was exhausted [91]. Further investigation ...
One population of progenitor cells, fate 1, likely corresponds to the embryonic precursors of adult neural stem cells33 that are biased to generate astroependymal cells and dentate granule neurons as early as E9.5. The second precursor cell population, fate 2, mainly contains oligodendrocyte ...