it is preferentially expressed on CD45RO+cells in the CD8+compartment. CD27 also appears to be a potential marker for memory B cells. It exists as both a disulfide-linked dimer on the cell surface and as a soluble 32 kDa pr...
B cellsB cells play a key role in humoral immune responses by producing antibodies. Although there are numerous research on memory B cells definition markers and cytokines on B cell development, different studies have yielded contradictory conclusions due to species studied, the different cells and ...
it is preferentially expressed on CD45RO+cells in the CD8+compartment. CD27 also appears to be a potential marker for memory B cells. It exists as both a disulfide‑linked dimer on the cell surface and as a soluble protein found in serum. Human CD27 is a 260 amino acid (aa) protein...
Immunosenescence, i.e. the aging-associated decline of the capacity of the immune system, is characterized by several distinct changes in the number and functions of the immune cells. In the case of B cells, the total number of CD19+ B cells is lower in
17 网络出版地址:http:/ /kns. cnki. net/kcms/detail/34. 1073. R. 20200520. 1453. 003. html弥漫大 B 细胞淋巴瘤中 CD27 的表达及临床意义葛晓雯,朱娜,姚家美,高峰,曾海英,栾丽娟,纪元,谭云山,侯英勇摘要:目的 探讨弥漫大 B 细胞淋巴瘤(diffuse large B cell lymphoma,DLBCL)中 CD27 的表达及其...
expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T ...
expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T ...
Cell-surfaceCD27is a useful marker of human memory B cells (Agematsu et al., 2000), since essentially all circulating CD27+B cells display hypermutated rearrangedVHgenes, while no mutations are identified in CD27−B cells. According to CD27 expression, CD19+blood B cells were grouped into...
"CD27: a memory B-cell marker." Immunology today 21.5 (2000): 204-206. 4.Van De Ven, Koen, and Jannie Borst. "Targeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potential." Immunotherapy 7.6 (2015): 655-667. 5.Claus, Christina, et al. "...
究对象外周血中未活化B细胞(CD19~CD27一),记忆性B细胞(CD19CD27)和浆 母细胞(CD19~CD27) 的比率,分析这3组B细胞亚群和CD19平均荧光强度与类风湿因子(RF),抗Ⅱ型 胶原(cⅡ)抗体和抗环 瓜氨酸(CCP)抗体及临床表现的关系.结果①RA与正常对照比较未活化B细胞和 ...