Clinical evidence suggests that elevated CD27 expression in T cells within the bone marrow serves as a negative prognostic marker for MM survival. Data analysis from the GEO database has demonstrated a strong association between MM-derived CD27 and the immune response, as well as the ...
it is preferentially expressed on CD45RA+cells. In contrast, it is preferentially expressed on CD45RO+cells in the CD8+compartment. CD27 also appears to be a potential marker for memory B cells. It exists as both a disulfide‑linked dimer on the cell surface and as a soluble protei...
on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells throu...
on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through...
Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic...
on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through...
**P < .01. E, endothelial cells; Endo, endothelial cells (CD31+CD144+ESAM+Kit–); FC, fold change; H, hematopoietic clusters. To identify new markers of embryonic HSCs and pre-HSCs, we analyzed Tnfrsf7, a gene in cluster 3 that encodes a BM HSC marker, CD27.15,16 CD27 is a ...
Cell-surfaceCD27is a useful marker of humanmemory B cells(Agematsu et al., 2000), since essentially all circulatingCD27+B cells display hypermutated rearrangedVHgenes, while no mutations are identified in CD27−B cells. According to CD27 expression,CD19+blood B cells were grouped into CD27...
on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through...
(4). CD27 is expressed on subsets of T and B cells. The expression of CD27 is upregulated upon T cell activation. Although CD27 appears to be a marker for human memory B cells, it is only expressed in a small population of mouse B cells in germinal centers and at sites of B ...