CD24最初被认为是B细胞的标记物,在B细胞分化早期阶段表达,同时对淋巴细胞成熟、神经系统发育及生理状态下的组织更新起到重要的作用。CD24主要表达于造血系统的细胞、神经组织以及一些特定的上皮细胞,同时也见于大多实体肿瘤、炎症组织以及自身免疫性疾病的某些细胞。众多研究发现,CD24在生理与病理状态下具有完全相反...
CD24, also known as heat stable antigen (HSA), is a heavily and variably glycosylated 35‑60 kDa GPI-linked sialoprotein that is expressed on B cells, T cells, keratinocytes, and myofiber synaptic nuclei and is up‑regulated in a wide variety of cancers. It is also a marker for exoso...
CD24 is an independent prognostic marker of survival in nonsmall cell lung cancer patients. Br J Cancer. 2003; 88 :231–236. doi: 10.1038/sj.bjc.6600702. [ Cross Ref ]Kristiansen, G, Schlüns, K, Yongwei, Y, Denkert, C, Dietel, M, Petersen, I (2003b) CD24 is an independent ...
CD24, also known as heat stable antigen (HSA), is a heavily and variably glycosylated 35‑60 kDa GPI-linked sialoprotein that is expressed on B cells, T cells, keratinocytes, and myofiber synaptic nuclei and is up‑regulated in a wide variety of cancers. It is also a marker for exoso...
J Cell Biochem 45: 156 – 161 Pirruccello SJ, Lang MS (1990) Differential expression of CD24-related epitopes in mycosis fungoides/Sezary syndrome: a potential marker for circulating Sezary cells. Blood 76: 2343 – 2347 Pirruccello SJ, LeBien TW (1986) The human B cell-associated antigen ...
Expression of a B-cell marker, CD24, on nasopharyngeal carcinoma cells Int J Cancer, 60 (1995), pp. 562-566 CrossrefView in ScopusGoogle Scholar 25 LR Huang, HC Hsu Cloning and expression of CD24 gene in human hepatocellular carcinoma: a potential early tumor marker gene correlates with ...
We recently identified the SCLC surface antigen Cluster-4 (CL-4) to be identical to the B cell differentiation marker CD24, except for one amino acid residue. The CD24/CL-4 antigen is highly expressed on SCLC, but rarely on NSCLC cells. In order to investigate the influence of the ...
neural cells, and epithelial cells. CD24 is widely used to delineate stages of lymphocyte development (1-3). It also binds to Siglec-10 in humans or Siglec-G in mice (4,5). CD24 is frequently used as a marker to identify and isolate cancer stem cells in various cancer types (6,7)...
CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulat...
CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulat...