Findings Neural stem-cell marker genes, including CD44, NES, and PROM1, are generally downregulated in IDH-mutant gliomas and IDH1R132H-heterozygous spheroid growth compared respectively with IDH-wildtype gliomas and IDH1R132H-hemizygous spheroid growth, in agreement with their negative associations ...
neural cells, and epithelial cells. CD24 is widely used to delineate stages of lymphocyte development (1-3). It also binds to Siglec-10 in humans or Siglec-G in mice (4,5). CD24 is frequently used as a marker to identify and isolate cancer stem cells in various cancer types (6,7)...
and myofiber synaptic nuclei and is up‑regulated in a wide variety of cancers. It is also a marker for exosomes released into the urine and amniotic fluid. CD24 binds to P-Selectin on activated platelets and vascular endothelial cells. CD24 ligation induces tumor cell apoptosis and is impor...
[3] Aroldi, Andrea,et al. "CD24/Siglec-10 Don't Eat Me Signal Blockade Is a Potential Immunotherapeutic Target in Mantle-Cell Lymphoma." Blood 138. Supplement 1 (2021): 2276-2276. [4] Shapira, Shiran,et al. "Integrase-derived peptides together with CD24-targeted lentiviral particles ...
and myofiber synaptic nuclei and is up‑regulated in a wide variety of cancers. It is also a marker for exosomes released into the urine and amniotic fluid. CD24 binds to P-Selectin on activated platelets and vascular endothelial cells. CD24 ligation induces tumor cell apoptosis and is impor...
20/21, 10117 Berlin, Germany Originally identified as a B-cell marker, expression of the cell surface molecule CD24 has meanwhile been observed in a variety of human malignancies. It appears to function as a ligand of P-Selectin, an adhesion molecule that is present in activated platelets ...
Multidisciplinary Respiratory Medicine 2013, 8:65 http://www.mrmjournal.com/content/8/1/65 ORIGINAL RESEARCH ARTICLE Open Access CD24+/CD38- as new prognostic marker for non-small cell lung cancer Feridoun Karimi-Busheri1,2*, Aghdass Rasouli-Nia2, Victoria Zadorozhny1 and Habib Fakhrai1 ...
This function is based on the negative binomial test of differential expression over cell clusters. The marker genes of a certain cluster were defined by significantly high expression over the other clusters in the sample. The p-value < 0.01 was used to select the signature gene set. The...
cellsusingthecellsurfacemarkerCD44.StemCells.2009;27(5):1006-1020. [2]PlentzRR,BaratS,ChenX,etal.Notchandwnt-betacateninpathways astargetsof-secretaseinhibitorIX(GSI)mediatedtherapyinCD44+γ gastriccancer(GC)cells.JClinOncol.2016;34(4):99. [3]ChenW,ZhangX,ChuC,etal.IdentificationofCD44+cancer...
binding to Siglec-10 and preventing phagocytosis.3 It is known as a marker of cancer cell stemness and dysregulates numerous signaling pathways involved in proliferation, invasion, and metastasis.4 The presence of CD24 has been strongly correlated to poor clinical outcome for multiple tumor types....