(1994). CD27: marker and mediator of T-cell activation? Immunol Today 15, 307-311.Hintzen, R. Q., J. Jong, S. M. Lens, and R. A. W. van Lier. 1994. CD27: marker and mediator of T cell activation. Immunol. Today 15: 307-311....
expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T ...
expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T ...
expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T ...
Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70. CD27-binding...
expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T ...
it is preferentially expressed on CD45RO+cells in the CD8+compartment. CD27 also appears to be a potential marker for memory B cells. It exists as both a disulfide‑linked dimer on the cell surface and as a soluble protein found in serum. Human CD27 is a 260 amino acid (aa) protein...
it is preferentially expressed on CD45RO+cells in the CD8+compartment. CD27 also appears to be a potential marker for memory B cells. It exists as both a disulfide-linked dimer on the cell surface and as a soluble 32 kDa pr...
Cell-surfaceCD27is a useful marker of human memory B cells (Agematsu et al., 2000), since essentially all circulating CD27+B cells display hypermutated rearrangedVHgenes, while no mutations are identified in CD27−B cells. According to CD27 expression, CD19+blood B cells were grouped into...
cell activation. Upon activation, naive CD4+ and CD8+ T cells transiently upregulate the expression of CD27. Activated T cells proteolytically shed CD27 from the cell surface, thereby giving rise to circulating soluble CD27 that can serve as a diagnostic marker of T-cell activation. Terminally ...