NF-κB is involved in the CCL2 expression induced by BRD4 Fig. 6: NF-κB is required for BRD4-induced CCL2. Full size image Macrophages activated by CCL2 stimulate tumor progression Fig. 7: BRD4-upregulated CCL2 activates TAMs. Full size image ...
Among the pathways implicated in inflammation, hallmark “TNFA signaling via NFKB” was significantly enriched in A3250 compared to MBA-MB-231, IBC3 and SUM149 (Fig. 3d). Hallmark “IL6 JAK STAT3 signaling” was significantly enriched in A3250 compared to MDA-MB-231 and IBC3 (Fig. 3d)...
CVC restores the hepatic immune cell landscape by inhibiting profibrotic gene transcription via the CCR2-STAT1/NFkB/ERK signaling pathways.Yangkun GuoChong ZhaoWenting DaiBowen WangEnjiang LaiYang XiaoChengwei TangJinhang GaoGut;Journal of British Society of Gasteroenterology...
The protein expression of ALPK1, NFkB and lectin was up‐regulated in glucose‐treated HK‐2 cells. Knockdown of ALPK1 reduced CCL2 and CCL5 mRNA levels, whereas overexpressed ALPK1 increased CCL2 and CCL5 in cultured kidney cells. Taken together, these results show that high glucose ...
人核转录因子(NF-kB)ELISA试剂盒 人红霉素-N-脱酶(ERND)ELISA试剂盒 人可溶性CD80(sCD80)ELISA试剂盒 人可溶性CD163分子(sCD163)ELISA试剂盒 人可溶性FMS样酪氨酸激酶1(sFlt-1)ELISA试剂盒 人可溶性半乳糖苷结合凝集素3(Lgals3)ELISA试剂盒 人可溶性尿激酶型纤溶酶原物受体(suPAR)ELISA试剂盒 人可溶性髓系细胞...
摘要:背景银屑病是一种常见的慢性炎症性皮肤病,其病因和发病机制尚不清楚,目前认为是一种在多基因遗传背景下、受多种内外环境因素刺激和诱导的慢性复发性炎症性皮肤病,以角质形成细胞(keratinocyte, KC)过度增生、新生血管形成、炎细胞浸润为其组织病理转变的三要素。在银屑病的组织病理变化中真皮血管的异常最先发生,...
4F). These data suggested that the PI3K/Akt and NF-κB signaling pathways are involved in the CCL2-induced paclitaxel resistance of ovarian cancer cells. Download: Download high-res image (410KB) Download: Download full-size image Fig. 4. Involvement of the PI3K/Akt and NF-κB pathways in...
S-294. THE INVOLVEMENT OF ACTIVATED NF-kB AND CCL2 IN THE DEVELOPMENT OF DIABETIC NEUROPATHIC PAINY ZhangY RodriguezM C GitlinK Candiotti
单核细胞趋化蛋白1MCP1+CCL2与肿瘤关系的研究进展
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